AKT1 (phospho Ser473) antibody [104A282] | GeneTex GTX11901 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

AKT1 (phospho Ser473) antibody [104A282]

catalog :

GTX11901

quantity :

50.00μg

price :

289 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

104A282

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 2

Reference
Matsuda N, Takano Y, Kageyama S, Hatakeyama N, Shakunaga K, Kitajima I, et al. Silencing of caspase-8 and caspase-3 by RNA interference prevents vascular endothelial cell injury in mice with endotoxic shock. Cardiovasc Res. 2007;76:132-40 pubmed
Chen Y, Cheng Y, Hung A, Wu Y, Hou M, Tyan Y, et al. The synthetic flavonoid WYC02-9 inhibits cervical cancer cell migration/invasion and angiogenesis via MAPK14 signaling. Gynecol Oncol. 2013;131:734-43 pubmed publisher

product information

Catalog No :

GTX11901

Product Name :

AKT1 (phospho Ser473) antibody [104A282]

Host Species :

Mouse

Clonality :

Monoclonal

Antigen Modification :

Phosphorylated

Product Type :

Primary antibody

Size :

50.00μg

List Price :

289 USD

list of Pubmed id :

17601517,24145114

Clone :

104A282

Isotype :

IgG1

Product Description :

Mouse monoclonal antibody [104A282] to Akt1 (phospho Ser473)

CrossReactivity :

Hu, Ms

Background :

The Akt family of serine/threonine protein kinases (also called protein kinase B/PKB) plays a key role in insulin signaling, cellular survival, and transformation. Akt1 is activated by phosphorylation on residues threonine 308 and Serine 473. Thr308, in the catalytic domain, is phosphorylated by the protein kinase PDK1, and Ser473, in the COOH-terminal regulatory domain, is phosphorylated by putative serine 473 kinase. To date, a couple of proteins have been shown to physically interact with PKB.

Immunogen :

Synthetic peptide (Human).

Buffer :

Preservative: 0.02% Sodium Azide; Constituents: PBS

Uses :

ICC/IF, IP, WB

Concentration :

0.5mg/ml

General References :

Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.