GPX1 antibody | GeneTex GTX116040 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

GPX1 antibody

catalog :

GTX116040

quantity :

100.00μl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; fig 3	Mowry A, Kavazis A, Sirman A, Potts W, Hood W. Reproduction Does Not Adversely Affect Liver Mitochondrial Respiratory Function but Results in Lipid Peroxidation and Increased Antioxidants in House Mice. PLoS ONE. 2016;11:e0160883 pubmed publisher
	Sultan C, Saackel A, Stank A, Fleming T, Fedorova M, Hoffmann R, et al. Impact of carbonylation on glutathione peroxidase-1 activity in human hyperglycemic endothelial cells. Redox Biol. 2018;16:113-122 pubmed publisher
	Hyatt H, Zhang Y, Hood W, Kavazis A. Physiological, mitochondrial, and oxidative stress differences in the presence or absence of lactation in rats. Reprod Biol Endocrinol. 2018;16:2 pubmed publisher

product information

Catalog No :

GTX116040

Product Name :

GPX1 antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μl

list of Pubmed id :

25541286

Isotype :

IgG

Product Description :

Rabbit Polyclonal antibody to GPX1 (glutathione peroxidase 1)

CrossReactivity :

Hu, Ms, Rat

Background :

This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]

Immunogen :

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GPX1. The exact sequence is proprietary.

Buffer :

0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Uses :

ICC/IF, IHC-P, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Image Legend_4 :

Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Glutathione peroxidase 1(GTX116040) antibody at 1:200 dilution.

Image Legend_5 :

Sample (30 ug of whole cell lysate) A: Molt-4 (GTX27912) B: Raji 12% SDS PAGE GTX116040 diluted at 1:1000