E-Cadherin antibody [DECMA-1] | GeneTex GTX11512 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

E-Cadherin antibody [DECMA-1]

catalog :

GTX11512

quantity :

100.00μl

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

DECMA-1

reactivity :

human, mouse, dogs

application :

western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; dogs; 1:500; loading ...; fig 4a	Hart K, Tan J, Siemers K, Sim J, PRUITT B, Nelson W, et al. E-cadherin and LGN align epithelial cell divisions with tissue tension independently of cell shape. Proc Natl Acad Sci U S A. 2017;114:E5845-E5853 pubmed publisher

product information

Catalog No :

GTX11512

Product Name :

E-Cadherin antibody [DECMA-1]

Host Species :

Rat

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μl

Clone :

DECMA-1

Isotype :

IgG1

Product Description :

Rat monoclonal [DECMA - 1] to E Cadherin

CrossReactivity :

Hu, Ms, Dog, Cat

Background :

Cell-cell interactions during embryonic development and in tissue organization involve specific cell-adhesion molecules (CAMs) that are functionally defined by antibodies that interfere with cell-cell adhesion. CAMs are expressed on early embryonic cells and persist in derivatives of all three germ layers. The best characterized CAMs are N-CAM (neural CAM) and L-CAM (liver CAM). The protein Uvomorulin, initially identified in embryonal carcinoma, is identical to L-CAM, E-Cadherin, Cell CAM 80/120 and ARC-1, each of which have been characterized in different systems. E-Cadherin has been characterized as a 120 kDa cell surface glycoprotein from which an 84 kDa fragment can be released by trypsin digestion in the presence of Ca 2+ .

Immunogen :

Mouse embryonal carcinoma cell line PCC4 Aza RI.

Buffer :

Preservative: 15mM Sodium Azide; Constituents: Raw Ascites

Uses :

ICC/IF, IHC-Fr, IP, WB

Concentration :

4mg/ml

General References :

Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.