Tropomyosin 1 antibody | GeneTex GTX113857 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

Tropomyosin 1 antibody

catalog :

GTX113857

quantity :

100.00μl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry - paraffin section

product information

Catalog No :

GTX113857

Product Name :

Tropomyosin 1 antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μl

list of Pubmed id :

21715321,25259860

Product Description :

Rabbit Polyclonal antibody to Tropomyosin 1 (tropomyosin 1 (alpha))

CrossReactivity :

Hu, Ms, Pig, Rat

Background :

This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by RefSeq]

Immunogen :

Recombinant protein encompassing a sequence within the center region of human Tropomyosin 1. The exact sequence is proprietary.

Buffer :

0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Uses :

IHC-P, WB

Concentration :

0.91mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Image Legend_4 :

Sample (30 ug of whole cell lysate) A: A431 (GTX27909) 12% SDS PAGE GTX113857 diluted at 1:1000

Image Legend_5 :

Tropomyosin 1 antibody detects Tropomyosin 1 protein at cytosol on mouse muscle by immunohistochemical analysis. Sample: Paraffin-embedded mouse muscle. Tropomyosin 1 antibody (GTX113857) dilution: 1:500.

Image Legend_6 :

Tropomyosin 1 antibody detects Tropomyosin 1 protein at cytosol on mouse vein by immunohistochemical analysis. Sample: Paraffin-embedded mouse vein. Tropomyosin 1 antibody (GTX113857) dilution: 1:500.