Grp78 antibody | GeneTex GTX113340 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

Grp78 antibody

catalog :

GTX113340

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

citations: 9

Reference
Wang S, Cheng C, Chen C, Chan H, Chen H, Tang P, et al. Acute Heat Stress Changes Protein Expression in the Testes of a Broiler-Type Strain of Taiwan Country Chickens. Anim Biotechnol. 2019;30:129-145 pubmed publisher
Kung P, Hsieh P, Lin Y, Lee J, Chen I, Wu C. HPW-RX40 prevents human platelet activation by attenuating cell surface protein disulfide isomerases. Redox Biol. 2017;13:266-277 pubmed publisher
Lin S, Yang L, Shi H, Du W, Qi Y, Qiu C, et al. Endoplasmic reticulum-targeting photosensitizer Hypericin confers chemo-sensitization towards oxaliplatin through inducing pro-death autophagy. Int J Biochem Cell Biol. 2017;87:54-68 pubmed publisher
Hsu H, Lin T, Lu M, Leng P, Tsao S, Wu Y. Fucoidan induces Toll-like receptor 4-regulated reactive oxygen species and promotes endoplasmic reticulum stress-mediated apoptosis in lung cancer. Sci Rep. 2017;7:44990 pubmed publisher
Kim J, La Gamma E, Estabrook T, Kudrick N, Nankova B. Whole genome expression profiling associates activation of unfolded protein response with impaired production and release of epinephrine after recurrent hypoglycemia. PLoS ONE. 2017;12:e0172789 pubmed publisher
Chiang W, Chan P, Wissinger B, Vincent A, Skorczyk Werner A, KrawczyÅ„ski M, et al. Achromatopsia mutations target sequential steps of ATF6 activation. Proc Natl Acad Sci U S A. 2017;114:400-405 pubmed publisher
Hsieh Y, Lo H, Yang P. EZH2 inhibitors transcriptionally upregulate cytotoxic autophagy and cytoprotective unfolded protein response in human colorectal cancer cells. Am J Cancer Res. 2016;6:1661-80 pubmed
Barel M, Harduin Lepers A, Portier L, Slomianny M, Charbit A. Host glycosylation pathways and the unfolded protein response contribute to the infection by Francisella. Cell Microbiol. 2016;18:1763-1781 pubmed publisher
Liong S, Lappas M. Endoplasmic reticulum stress regulates inflammation and insulin resistance in skeletal muscle from pregnant women. Mol Cell Endocrinol. 2016;425:11-25 pubmed publisher

product information

Catalog Number :

GTX113340

Product Name :

Grp78 antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary Antibody

list of Pubmed id :

24359494,24011924,23572564,24984699,25259860,25242635,25242635,25807986,26362846,26029869,25849717,26902174,27185209,27648357,28028229,28392376,28332554,28600983,29553885

Background :

When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM]