PKC beta antibody | GeneTex GTX113252 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

PKC beta antibody

catalog :

GTX113252

quantity :

100.00μl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 3	Zhu D, Tang R, Lv L, Wen Y, Liu H, Zhang X, et al. Interleukin-1Î² mediates high glucose induced phenotypic transition in human aortic endothelial cells. Cardiovasc Diabetol. 2016;15:42 pubmed publisher

product information

Catalog No :

GTX113252

Product Name :

PKC beta antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μl

list of Pubmed id :

25135933

Isotype :

IgG

Product Description :

Rabbit Polyclonal antibody to PKC beta (protein kinase C, beta)

CrossReactivity :

Background :

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Immunogen :

Recombinant protein encompassing a sequence within the center region of human PKC beta. The exact sequence is proprietary.

Buffer :

0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Uses :

ICC/IF, IHC-P, WB, Functional Assay

Concentration :

0.63mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.