Glucocorticoid Receptor antibody | GeneTex GTX113208 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

Glucocorticoid Receptor antibody

catalog :

GTX113208

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

GTX113208

Product Name :

Glucocorticoid Receptor antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary Antibody

Background :

The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. [provided by RefSeq]