GADD153 antibody [N1C3] | GeneTex GTX112827 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

GADD153 antibody [N1C3]

catalog :

GTX112827

quantity :

100.00μl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry - paraffin section

product information

Catalog No :

GTX112827

Product Name :

GADD153 antibody [N1C3]

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μl

list of Pubmed id :

24984699,25807986

Isotype :

IgG

Product Description :

Rabbit Polyclonal antibody to GADD153 (DNA-damage-inducible transcript 3)

CrossReactivity :

Hu, Ms

Background :

This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq]

Immunogen :

Full length human GADD153 Recombinant protein.

Buffer :

1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Uses :

IHC-P, WB, IHC-R

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.