This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
MAP2 antibody [AP20]
catalog :
GTX11268
quantity :
50.00μl
price :
289 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AP20
reactivity :
mouse, rat, cow
application :
western blot, immunocytochemistry
product information
Catalog No :
GTX11268
Product Name :
MAP2 antibody [AP20]
Host Species :
Mouse
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
50.00μl
List Price :
289 USD
Clone :
AP20
Isotype :
IgG1
Product Description :
Mouse monoclonal [AP - 20] to MAP2
CrossReactivity :
Ms, Cow, Rat, Ql, Slm, Xl
Background :
MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.
Immunogen :
Bovine protein.
Specificity :
The antibody localizes the high molecular weight forms of MAP2 namely MAP2a and MAP2b, but shows no reactivity with MAP2c. No cross-reactivity is observed with MAP1, MAP5, tubulin, or tau.
Buffer :
Preservative: 15mM Sodium Azide
Uses :
ICC/IF, WB
Concentration :
3.5mg/ml
General References :
Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
company information
GeneTex
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