alpha Tubulin 4a antibody | GeneTex GTX112141 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

alpha Tubulin 4a antibody

catalog :

GTX112141

quantity :

100.00μl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, chicken

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; fig 2	Mowry A, Kavazis A, Sirman A, Potts W, Hood W. Reproduction Does Not Adversely Affect Liver Mitochondrial Respiratory Function but Results in Lipid Peroxidation and Increased Antioxidants in House Mice. PLoS ONE. 2016;11:e0160883 pubmed publisher
immunocytochemistry; human; fig 3	Chen N, Chyau C, Lee Y, Tseng H, Chou F. Promotion of mitotic catastrophe via activation of PTEN by paclitaxel with supplement of mulberry water extract in bladder cancer cells. Sci Rep. 2016;6:20417 pubmed publisher
	Zhang P, Csaki L, Ronquillo E, Baufeld L, Lin J, Gutiérrez A, et al. Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis. J Clin Invest. 2019;129:281-295 pubmed publisher
	von Morgen P, Burdova K, Flower T, O Reilly N, Boulton S, Smerdon S, et al. MRE11 stability is regulated by CK2-dependent interaction with R2TP complex. Oncogene. 2017;36:4943-4950 pubmed publisher
	Guo J, Hsu H, Tyan S, Li F, Shew J, Lee W, et al. Serglycin in tumor microenvironment promotes non-small cell lung cancer aggressiveness in a CD44-dependent manner. Oncogene. 2017;36:2457-2471 pubmed publisher
	Wang S, Huang C, Shen C, Lin L, Zhao P, Chen S, et al. Gene Expression and DNA Methylation Status of Glutathione S-Transferase Mu1 and Mu5 in Urothelial Carcinoma. PLoS ONE. 2016;11:e0159102 pubmed publisher

product information

Catalog No :

GTX112141

Product Name :

alpha Tubulin 4a antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μl

list of Pubmed id :

24444450,23127597,23603493,24211270,24405781,24675091,24723343,24812029,24998975,25227736,25355692,25639359,25596698,25656647,25557231,25909282

Isotype :

IgG

Product Description :

Rabbit Polyclonal antibody to alpha Tubulin 4a (tubulin alpha-4A chain)

CrossReactivity :

Hu, Ms, Chk, Dm, Rat

Background :

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. [provided by RefSeq]

Immunogen :

Recombinant protein encompassing a sequence within the center region of human alpha Tubulin 4a. The exact sequence is proprietary.

Buffer :

1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

Uses :

ICC/IF, IHC-P, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Image Legend_4 :

alpha Tubulin 4a antibody detects alpha Tubulin 4a protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with alpha Tubulin 4a antibody (GTX112141) diluted by 1:20000.

Image Legend_5 :

Immunohistochemical analysis of paraffin-embedded U373 xenograft, using alpha Tubulin 4a(GTX112141) antibody at 1:500 dilution.

Image Legend_6 :

Sample (30 ug of cell lysate) A: HeLa B: HeLa cytosol fraction C: HeLa nucleus fraction 10% SDS PAGE GTX112141 diluted at 1:10000

Image Legend_7 :

alpha Tubulin 4a antibody detects alpha Tubulin 4a protein by western blot analysis. A. 20 μg 293T whole cell lysate/extract B. 10 μg 293T whole cell lysate/extract C. 5 μg 293T whole cell lysate/extract 10 % SDS-PAGE alpha Tubulin 4a antibody (GTX112141) dilution: 1:10000

Image Legend_8 :

alpha Tubulin 4a antibody detects alpha Tubulin 4a protein by western blot analysis. A. 30 μg Drosophila lysate/extract. 10 % SDS-PAGE. alpha Tubulin 4a antibody (GTX112141) dilution: 1:2000

Image Legend_9 :