ERBB4 antibody [C1C3] | GeneTex GTX111276 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

ERBB4 antibody [C1C3]

catalog :

GTX111276

quantity :

100.00μl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

product information

Catalog No :

GTX111276

Product Name :

ERBB4 antibody [C1C3]

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μl

list of Pubmed id :

21364123

Isotype :

IgG

Product Description :

Rabbit Polyclonal antibody to ERBB4 (v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian))

CrossReactivity :

Hu, Ms

Background :

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq]

Immunogen :

Recombinant protein encompassing a sequence within the C-terminus region of human ERBB4. The exact sequence is proprietary.

Buffer :

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Uses :

ICC/IF, IHC-P, IP, WB

Concentration :

0.95mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Image Legend_4 :

ERBB4 antibody [C1C3] detects ERBB4 protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: MCF-7 cells were fixed in ice-cold MeOH for 5 min. Green: ERBB4 protein stained by ERBB4 antibody [C1C3] (GTX111276) diluted at 1:500. Blue: Hoechst 33342 staining.

Image Legend_5 :

ERBB4 antibody [C1C3] immunoprecipitates ERBB4 protein in IP experiments. IP samples: MCF-7 whole cell extract A. Control with 4 μg of preimmune Rabbit IgG B. Immunoprecipitation of ERBB4 protein by 4 μg ERBB4 antibody [C1C3] (GTX111276) 5 % SDS-PAGE The immunoprecipitated ERBB4 protein was detected by ERBB4 antibody [C1C3] (GTX111276) diluted at 1:500. [EasyBlot anti-rabbit IgG (GTX221666-01) was used as a secondary reagent]