ATP6V1A antibody | GeneTex GTX110815 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

ATP6V1A antibody

catalog :

GTX110815

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 3g	Matsumoto A, Pasut A, Matsumoto M, Yamashita R, Fung J, Monteleone E, et al. mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide. Nature. 2017;541:228-232 pubmed publisher
	Hashimoto Y, Shirane M, Nakayama K. TMEM55B contributes to lysosomal homeostasis and amino acid-induced mTORC1 activation. Genes Cells. 2018;23:418-434 pubmed publisher
	Wang A, Carraro Lacroix L, Owen C, Gao B, Corey P, Tyrrell P, et al. Activity-independent targeting of mTOR to lysosomes in primary osteoclasts. Sci Rep. 2017;7:3005 pubmed publisher
	Henderson M, Wirak G, Zhang Y, Dai F, Ginsberg S, Dolzhanskaya N, et al. Neuronal ceroid lipofuscinosis with DNAJC5/CSPÎ± mutation has PPT1 pathology and exhibit aberrant protein palmitoylation. Acta Neuropathol. 2016;131:621-37 pubmed publisher

product information

Catalog Number :

GTX110815

Product Name :

ATP6V1A antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary Antibody

list of Pubmed id :

25561175,26659577,25567907,28024296,28592812,29644770

Background :

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues. Transcript variants derived from alternative polyadenylation exist. [provided by RefSeq]