p38 MAPK antibody [N1C3-2] | GeneTex GTX110720 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

p38 MAPK antibody [N1C3-2]

catalog :

GTX110720

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

citations: 5

Reference
Sarin N, Engel F, Rothweiler F, Cinatl J, Michaelis M, Frötschl R, et al. Key Players of Cisplatin Resistance: Towards a Systems Pharmacology Approach. Int J Mol Sci. 2018;19: pubmed publisher
Yeh C, Chen C, Leu Y, Lin M, Chiu M, Wang S. The effects of artocarpin on wound healing: in vitro and in vivo studies. Sci Rep. 2017;7:15599 pubmed publisher
Lin J, Chang Y, Chen Y, Shen B, Yang D. Molecular mechanisms of the effects of the ethanolic extract of Muntingia calabura Linn. fruit on lipopolysaccharide-induced pro-inflammatory mediators in macrophages. Food Funct. 2017;8:1245-1253 pubmed publisher
Chen P, Chang C, Shih C, Cheng C, Lin C, Lee C, et al. The miR-204-3p-targeted IGFBP2 pathway is involved in xanthohumol-induced glioma cell apoptotic death. Neuropharmacology. 2016;110:362-375 pubmed publisher
Chen C, Lin M, Liang C, Wang S. The Anti-Inflammatory Effects and Mechanisms of Eupafolin in Lipopolysaccharide-Induced Inflammatory Responses in RAW264.7 Macrophages. PLoS ONE. 2016;11:e0158662 pubmed publisher

product information

Catalog Number :

GTX110720

Product Name :

p38 MAPK antibody [N1C3-2]

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary Antibody

list of Pubmed id :

23664097,24083466,27487563,27414646,26317424,29142215,29518977,28232982

Background :

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]