Fumarate hydratase antibody [N2C2], Internal | GeneTex GTX110128 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

Fumarate hydratase antibody [N2C2], Internal

catalog :

GTX110128

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

citations: 1

Reference
Tseng C, Kuo W, Chan S, Chan H, Chang K, Wang L. Transketolase Regulates the Metabolic Switch to Control Breast Cancer Cell Metastasis via the α-Ketoglutarate Signaling Pathway. Cancer Res. 2018;78:2799-2812 pubmed publisher

product information

Catalog Number :

GTX110128

Product Name :

Fumarate hydratase antibody [N2C2], Internal

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary Antibody

list of Pubmed id :

25028521,29599405

Background :

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq]