Hsp90 alpha antibody | GeneTex GTX109753 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

Hsp90 alpha antibody

catalog :

GTX109753

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

African green monkey, human, rat

application :

western blot, immunocytochemistry

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 1:2000; loading ...; fig 9a, 10c	Cai H, Han B, Hu Y, Zhao X, He Z, Chen X, et al. Metformin attenuates the D‑galactose‑induced aging process via the UPR through the AMPK/ERK1/2 signaling pathways. Int J Mol Med. 2020;45:715-730 pubmed publisher
immunocytochemistry; African green monkey; fig 2	Tung H, Wei S, Lo H, Chao Y. Baculovirus IE2 Stimulates the Expression of Heat Shock Proteins in Insect and Mammalian Cells to Facilitate Its Proper Functioning. PLoS ONE. 2016;11:e0148578 pubmed publisher
	Fan C, Chen W, Chen L, Chen C, Hsu Y, Chua K, et al. Osteopontin-integrin engagement induces HIF-1Î±-TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer. Oncotarget. 2018;9:4998-5015 pubmed publisher
	Luu B, Wijenayake S, Malik A, Storey K. The regulation of heat shock proteins in response to dehydration in Xenopus laevis. Cell Stress Chaperones. 2018;23:45-53 pubmed publisher
	Chen X, Zhao X, Cai H, Sun H, Hu Y, Huang X, et al. The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKÎ²/AMPK pathways. Redox Biol. 2017;12:987-1003 pubmed publisher
	Chiang W, Chan P, Wissinger B, Vincent A, Skorczyk Werner A, KrawczyÅ„ski M, et al. Achromatopsia mutations target sequential steps of ATF6 activation. Proc Natl Acad Sci U S A. 2017;114:400-405 pubmed publisher
	Wu D, Chen T, Huang H, Lee H. TC-N19, a novel dual inhibitor of EGFR and cMET, efficiently overcomes EGFR-TKI resistance in non-small-cell lung cancer cells. Cell Death Dis. 2016;7:e2290 pubmed publisher

product information

Catalog Number :

GTX109753

Product Name :

Hsp90 alpha antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary Antibody

list of Pubmed id :

24161787,24211270,25269988,26215928,26206181,27362807,28028229,28499253,28676984,24623724,29435158

Background :

HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 (MIM 140572), a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM]