Bax antibody [N1N2], N-term | GeneTex GTX109683 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

Bax antibody [N1N2], N-term

catalog :

GTX109683

quantity :

100.00μl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 3	Fu X, Xie F, Dong P, Li Q, Yu G, Xiao R. High-Dose Fluoride Impairs the Properties of Human Embryonic Stem Cells via JNK Signaling. PLoS ONE. 2016;11:e0148819 pubmed publisher
western blot; human; 1:1000; fig 2	Xu Y, Wu D, Zheng W, Yu F, Yang F, Yao Y, et al. Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. Oncotarget. 2016;7:6146-58 pubmed publisher
	Wang Y, Zhu S, Wei W, Tu Y, Chen C, Song J, et al. Interleukin-6 knockout reverses macrophage differentiation imbalance and alleviates cardiac dysfunction in aging mice. Aging (Albany NY). 2020;12:20184-20197 pubmed publisher

product information

Catalog No :

GTX109683

Product Name :

Bax antibody [N1N2], N-term

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μl

list of Pubmed id :

24444450,23127597,23573126,23091557,21376104,21708241,22306340,24980118,25411358,25596698,25914533,25909282

Isotype :

IgG

Product Description :

Rabbit polyclonal antibody to BAX (BCL2-associated X protein)

CrossReactivity :

Hu, Rat

Background :

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq]

Immunogen :

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Bax. The exact sequence is proprietary.

Buffer :

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Uses :

ICC/IF, IHC-P, IP, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.

Image Legend_4 :

Bax antibody [N1N2], N-term immunoprecipitates BCL2-associated X protein in IP experiments. IP samples: MCF-7 whole cell extract A. Control with 4 μg of preimmune Rabbit IgG B. Immunoprecipitation of BCL2-associated X protein by 4 μg Bax antibody [N1N2], N-term (GTX109683) 15 % SDS-PAGE The immunoprecipitated BCL2-associated X protein was detected by Bax antibody [N1N2], N-term (GTX109683) diluted at 1:500. [EasyBlot anti-rabbit IgG (GTX221666-01) was used as a secondary reagent]