This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
Arginase 1 antibody
catalog :
GTX109242
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3k
Zhang D, Tang Z, Huang H, Zhou G, Cui C, Weng Y, et al. Metabolic regulation of gene expression by histone lactylation. Nature. 2019;574:575-580 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2f
Carmona Fontaine C, Deforet M, Akkari L, Thompson C, Joyce J, Xavier J. Metabolic origins of spatial organization in the tumor microenvironment. Proc Natl Acad Sci U S A. 2017;114:2934-2939 pubmed publisher
  • western blot; rat; loading ...; fig 6a
Wu J, Sun L, Li H, Shen H, Zhai W, Yu Z, et al. Roles of programmed death protein 1/programmed death-ligand 1 in secondary brain injury after intracerebral hemorrhage in rats: selective modulation of microglia polarization to anti-inflammatory phenotype. J Neuroinflammation. 2017;14:36 pubmed publisher
Hoover A, Hufnagel D, HARRIS W, Bullock K, Glass E, Liu E, et al. Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor progression in syngeneic murine models of ovarian cancer. BMC Cancer. 2020;20:970 pubmed publisher
Motterlini R, Nikam A, Manin S, Ollivier A, Wilson J, Djouadi S, et al. HYCO-3, a dual CO-releaser/Nrf2 activator, reduces tissue inflammation in mice challenged with lipopolysaccharide. Redox Biol. 2019;20:334-348 pubmed publisher
Shen P, Li Q, Ma J, Tian M, Hong F, Zhai X, et al. IRAK-M alters the polarity of macrophages to facilitate the survival of Mycobacterium tuberculosis. BMC Microbiol. 2017;17:185 pubmed publisher
Zhu Y, Zhang L, Lu Q, Gao Y, Cai Y, Sui A, et al. Identification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathy. Int J Mol Med. 2017;40:281-292 pubmed publisher
Pileri A, Agostinelli C, Sessa M, Quaglino P, Santucci M, Tomasini C, et al. Langerhans, plasmacytoid dendritic and myeloid-derived suppressor cell levels in mycosis fungoides vary according to the stage of the disease. Virchows Arch. 2017;470:575-582 pubmed publisher
Royo F, Moreno L, Mleczko J, Palomo L, Gonzalez E, Cabrera D, et al. Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism. Sci Rep. 2017;7:42798 pubmed publisher
Aalinkeel R, Mangum C, Abou Jaoude E, Reynolds J, Liu M, Sundquist K, et al. Galectin-1 Reduces Neuroinflammation via Modulation of Nitric Oxide-Arginase Signaling in HIV-1 Transfected Microglia: a Gold Nanoparticle-Galectin-1 "Nanoplex" a Possible Neurotherapeutic?. J Neuroimmune Pharmacol. 2017;12:133-151 pubmed publisher
Romano A, Parrinello N, Vetro C, Tibullo D, Giallongo C, La Cava P, et al. The prognostic value of the myeloid-mediated immunosuppression marker Arginase-1 in classic Hodgkin lymphoma. Oncotarget. 2016;7:67333-67346 pubmed publisher
Ghosh M, Xu Y, Pearse D. Cyclic AMP is a key regulator of M1 to M2a phenotypic conversion of microglia in the presence of Th2 cytokines. J Neuroinflammation. 2016;13:9 pubmed publisher
product information
Catalog Number :
GTX109242
Product Name :
Arginase 1 antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Product Type :
Primary Antibody
list of Pubmed id :
23514739,24658465,24966392,25134659,26480475,26112094,25516435,24303100,26757726,28028734,26285119,28211494,28196545,28321511,27637084,25183802,28627621,28835201,23997223,26451303
Background :
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. [provided by RefSeq]
company information
GeneTex
2456 Alton Pkwy
Irvine, CA92606
info@genetex.com
http://www.genetex.com
1-877-436-3839
headquarters: USA