This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
Cyclin D1 antibody [N1C3]
catalog :
GTX108624
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
citations: 8
Reference
Fan H, Hsieh Y, Li L, Chang C, Janoušková K, Ramani M, et al. Dehydroxyhispolon Methyl Ether, A Hispolon Derivative, Inhibits WNT/β-Catenin Signaling to Elicit Human Colorectal Carcinoma Cell Apoptosis. Int J Mol Sci. 2020;21: pubmed publisher
Wu Z, Huang W, Chen B, Bai P, Wang X, Xing J. Up-regulation of miR-124 inhibits invasion and proliferation of prostate cancer cells through mediating JAK-STAT3 signaling pathway. Eur Rev Med Pharmacol Sci. 2017;21:2338-2345 pubmed
Lin H, Lin M, Liao J, Wu T, Lee T, Mi F, et al. Antroquinonol, a Ubiquinone Derivative from the Mushroom Antrodia camphorata, Inhibits Colon Cancer Stem Cell-like Properties: Insights into the Molecular Mechanism and Inhibitory Targets. J Agric Food Chem. 2017;65:51-59 pubmed publisher
Chen P, Shen W, Shih C, Ho K, Cheng C, Lin C, et al. The CHAC1-inhibited Notch3 pathway is involved in temozolomide-induced glioma cytotoxicity. Neuropharmacology. 2017;116:300-314 pubmed publisher
Chen C, Liang C, Leu Y, Chen Y, Wang S. Viscolin Inhibits In Vitro Smooth Muscle Cell Proliferation and Migration and Neointimal Hyperplasia In Vivo. PLoS ONE. 2016;11:e0168092 pubmed publisher
Lu C, Chen S, Chang Y, Liu Y, Wu J, Lim Y, et al. Honokiol, a potential therapeutic agent, induces cell cycle arrest and program cell death in vitro and in vivo in human thyroid cancer cells. Pharmacol Res. 2017;115:288-298 pubmed publisher
Yen C, Chen J, Chang Y, Hsu Y, Chiu P, Shiue C, et al. Lovastatin causes FaDu hypopharyngeal carcinoma cell death via AMPK-p63-survivin signaling cascade. Sci Rep. 2016;6:25082 pubmed publisher
Yeh Y, Wang S, Yeh Y, Hsiao H, Li T. Rhapontigenin inhibits TGF-?-mediated epithelial?mesenchymal transition via the PI3K/AKT/mTOR pathway and is not associated with HIF-1? degradation. Oncol Rep. 2016;35:2887-95 pubmed publisher
product information
Catalog Number :
GTX108624
Product Name :
Cyclin D1 antibody [N1C3]
Host Species :
Rabbit
Clonality :
Polyclonal
Product Type :
Primary Antibody
list of Pubmed id :
24211270,24763086,26986649,27122225,27940017,26510776,27986595,27977759,27997180,28617558
Background :
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq]
company information
GeneTex
2456 Alton Pkwy
Irvine, CA92606
info@genetex.com
http://www.genetex.com
1-877-436-3839
headquarters: USA