CDC2 antibody [N1], N-term | GeneTex GTX108120 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

CDC2 antibody [N1], N-term

catalog :

GTX108120

quantity :

100.00μl

price :

299 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation, immunohistochemistry - paraffin section

citations: 3

Reference
Pan J, Nakade K, Huang Y, Zhu Z, Masuzaki S, Hasegawa H, et al. Suppression of cell-cycle progression by Jun dimerization protein-2 (JDP2) involves downregulation of cyclin-A2. Oncogene. 2010;29:6245-56 pubmed publisher
Cheung A, Ip J, Lung H, Wu J, Tsao S, Lung M. Polo-like kinase inhibitor Ro5203280 has potent antitumor activity in nasopharyngeal carcinoma. Mol Cancer Ther. 2013;12:1393-401 pubmed publisher
Chu C, Hsu P, Lo P, Scheer E, Tora L, Tsai H, et al. Protein kinase A-mediated serine 35 phosphorylation dissociates histone H1.4 from mitotic chromosome. J Biol Chem. 2011;286:35843-51 pubmed publisher

product information

Catalog No :

GTX108120

Product Name :

CDC2 antibody [N1], N-term

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μl

List Price :

299 USD

list of Pubmed id :

21852232,20802531,23686835

Isotype :

IgG

Product Description :

Rabbit Polyclonal antibody to CDC2 (cyclin-dependent kinase 1)

CrossReactivity :

Hu, Ms, Rat

Background :

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Immunogen :

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CDC2. The exact sequence is proprietary.

Buffer :

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Uses :

IHC-P, IP, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Image Legend_4 :

Sample (30 ug of whole cell lysate) A: PC-12 10% SDS PAGE GTX108120 diluted at 1:5000