RIP3 antibody | GeneTex GTX107574 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

RIP3 antibody

catalog :

GTX107574

quantity :

100.00μl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, proximity ligation assay

citations: 2

Published Application/Species/Sample/Dilution	Reference
proximity ligation assay; human; loading ...; fig 4a immunocytochemistry; human; loading ...; fig s6b immunohistochemistry; human; loading ...; fig 1c western blot; human; 1:1000; loading ...; fig 1d	Al Lamki R, Lu W, Manalo P, Wang J, Warren A, Tolkovsky A, et al. Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis. Cell Death Dis. 2016;7:e2287 pubmed publisher
western blot; human; fig 2	Huang Y, Chen Y, Lai Y, Cheng C, Lin T, Su Y, et al. Resveratrol alleviates the cytotoxicity induced by the radiocontrast agent, ioxitalamate, by reducing the production of reactive oxygen species in HK-2 human renal proximal tubule epithelial cells in vitro. Int J Mol Med. 2016;37:83-91 pubmed publisher

product information

Catalog No :

GTX107574

Product Name :

RIP3 antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μl

list of Pubmed id :

25909282

Isotype :

IgG

Product Description :

Rabbit Polyclonal antibody to RIP3 (receptor-interacting serine-threonine kinase 3)

CrossReactivity :

Hu, Ms

Background :

The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq]

Immunogen :

Recombinant protein encompassing a sequence within the center region of human RIP3. The exact sequence is proprietary.

Buffer :

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Uses :

ICC/IF, IHC-P, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Image Legend_4 :

Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using RIP3 (GTX107574) antibody at 1:200 dilution.