This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
TNFSF5 antibody
catalog :
GTX10507
quantity :
25.00μg
price :
289 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA
product information
Catalog No :
GTX10507
Product Name :
TNFSF5 antibody
Host Species :
Goat
Clonality :
Polyclonal
Product Type :
Primary antibody
Size :
25.00μg
List Price :
289 USD
Isotype :
IgG
Product Description :
Goat polyclonal to TNFSF5
CrossReactivity :
Hu
Background :
CD40 ligand (also known as CD154, TRAP, or gp39) is a 261 amino acid type II transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) superfamily. CD40L is expressed predominantly on activated CD4+ T lymphocytes. It is also found in other cell types (NK cells, mast cells, basophils, and eosinophils). Human and mouse CD40L share approximately 78% sequence identity. The receptor for CD40L is CD40. CD40, a type I transmembrane glycoprotein belonging to the TNF receptor family, is expressed on B lymphocytes, monocytes, dendritic cells, and thymic epithelium. Following interaction with CD40 ligand, CD40 mediates a number of major immunoregulatory functions central to the control of thymus-dependent humoral immunity and may be critical in the development of cell-mediated immune responses. Other biological actions include B cell homotypic adhesion, proliferation, immunoglobulin isotype switch, and secretion. The interaction of CD40 and CD40L also plays important roles in monocyte activation and dendritic cell maturation. Activation of CD40 inhibits the growth of certain B cell lymphomas and induces the death of transformed cells of mesenchymal or epithelial origin.
Immunogen :
Purified recombinant human CD40 ligand extracellular domain expressed in Escherichia coli.
Buffer :
Preservative: NoneConstituents: PBS
Uses :
ELISA, WB
Concentration :
0.1mg/ml
General References :
Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
company information
GeneTex
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