c-Myc antibody | GeneTex GTX103436 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

c-Myc antibody

catalog :

GTX103436

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

citations: 5

Reference
Seira N, Yamagata K, Fukushima K, Araki Y, Kurata N, Yanagisawa N, et al. Cellular density-dependent increases in HIF-1α compete with c-Myc to down-regulate human EP4 receptor promoter activity through Sp-1-binding region. Pharmacol Res Perspect. 2018;6:e00441 pubmed publisher
Yang J, Lee C, Cho H, Lu C, Kuo S, Wen Y, et al. ITR?284 modulates cell differentiation in human chronic myelogenous leukemia K562 cells. Oncol Rep. 2018;39:383-391 pubmed publisher
Lee Y, Chang W, Chen Y, Tsai Y, Chou Y, Tseng H, et al. Hsp90α Mediates BMI1 Expression in Breast Cancer Stem/Progenitor Cells through Facilitating Nuclear Translocation of c-Myc and EZH2. Int J Mol Sci. 2017;18: pubmed publisher
Lin H, Lin M, Liao J, Wu T, Lee T, Mi F, et al. Antroquinonol, a Ubiquinone Derivative from the Mushroom Antrodia camphorata, Inhibits Colon Cancer Stem Cell-like Properties: Insights into the Molecular Mechanism and Inhibitory Targets. J Agric Food Chem. 2017;65:51-59 pubmed publisher
Fan F, Wu H, Liu Z, Hou X, Chen W, Wang A, et al. Nuclear PKM2 expression, an independent risk factor for ER after curative resection of hepatocellular carcinoma. Biomed Pharmacother. 2016;84:1858-1864 pubmed publisher

product information

Catalog Number :

GTX103436

Product Name :

c-Myc antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary Antibody

list of Pubmed id :

26163148,26226629,27894667,25826088,27997180,28914785,29138846

Background :

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq]