Grp78 antibody [N2C1], Internal | GeneTex GTX102580 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

Grp78 antibody [N2C1], Internal

catalog :

GTX102580

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 1:2000; loading ...; fig 9g, 10d	Cai H, Han B, Hu Y, Zhao X, He Z, Chen X, et al. Metformin attenuates the D‑galactose‑induced aging process via the UPR through the AMPK/ERK1/2 signaling pathways. Int J Mol Med. 2020;45:715-730 pubmed publisher
	Chen X, Zhao X, Cai H, Sun H, Hu Y, Huang X, et al. The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKÎ²/AMPK pathways. Redox Biol. 2017;12:987-1003 pubmed publisher
	Cueno M, Saito Y, Ochiai K. Periodontal disease level-butyric acid amounts locally administered in the rat gingival mucosa induce ER stress in the systemic blood. Microb Pathog. 2016;94:70-5 pubmed publisher

product information

Catalog Number :

GTX102580

Product Name :

Grp78 antibody [N2C1], Internal

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary Antibody

list of Pubmed id :

26541671,28499253

Background :

When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM]