p63 antibody [N2C1], Internal | GeneTex GTX102425 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

p63 antibody [N2C1], Internal

catalog :

GTX102425

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

citations: 15

Reference
Kim D, Dollé M, Vermeij W, Gyenis A, Vogel K, Hoeijmakers J, et al. Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin. Aging Cell. 2020;19:e13072 pubmed publisher
O Brien V, Dorsey D, Hannan T, Hultgren S. Host restriction of Escherichia coli recurrent urinary tract infection occurs in a bacterial strain-specific manner. PLoS Pathog. 2018;14:e1007457 pubmed publisher
Pattison J, Melo S, Piekos S, Torkelson J, Bashkirova E, Mumbach M, et al. Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment. Nat Genet. 2018;50:1658-1665 pubmed publisher
Li H, Cuevas I, Zhang M, Lu C, Alam M, Fu Y, et al. Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load. J Clin Invest. 2018;128:4179-4191 pubmed publisher
Tata A, Kobayashi Y, Chow R, Tran J, Desai A, Massri A, et al. Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury. Cell Stem Cell. 2018;22:668-683.e6 pubmed publisher
Sang M, Nakamura M, Ogata T, Sun D, Shimozato O, Nikaido T, et al. Impact of RUNX2 gene silencing on the gemcitabine sensitivity of p53?mutated pancreatic cancer MiaPaCa?2 spheres. Oncol Rep. 2018;39:2749-2758 pubmed publisher
Tata P, Chow R, Saladi S, Tata A, Konkimalla A, Bara A, et al. Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity. Dev Cell. 2018;44:679-693.e5 pubmed publisher
Tamai R, Kobayashi Sakamoto M, Kiyoura Y. Extracellular galectin-1 enhances adhesion to and invasion of oral epithelial cells by Porphyromonas gingivalis. Can J Microbiol. 2018;64:465-471 pubmed publisher
Xiong Z, Ren S, Chen H, Liu Y, Huang C, Zhang Y, et al. PAX9 regulates squamous cell differentiation and carcinogenesis in the oro-oesophageal epithelium. J Pathol. 2018;244:164-175 pubmed publisher
He K, Sakai T, Tsukasaki Y, Watanabe T, Ikebe M. Myosin X is recruited to nascent focal adhesions at the leading edge and induces multi-cycle filopodial elongation. Sci Rep. 2017;7:13685 pubmed publisher
Jin H, Xie Q, Guo X, Xu J, Wang A, Li J, et al. p63? protein up-regulates heat shock protein 70 expression via E2F1 transcription factor 1, promoting Wasf3/Wave3/MMP9 signaling and bladder cancer invasion. J Biol Chem. 2017;292:15952-15963 pubmed publisher
Kim B, Coyaud E, Laurent E, St Germain J, Van de Laar E, Tsao M, et al. Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth. Mol Cell Proteomics. 2017;16:1864-1888 pubmed publisher
Reneker L, Wang L, Irlmeier R, Huang A. Fibroblast Growth Factor Receptor 2 (FGFR2) Is Required for Meibomian Gland Homeostasis in the Adult Mouse. Invest Ophthalmol Vis Sci. 2017;58:2638-2646 pubmed publisher
Sasaki Y, Tamura M, Takeda K, Ogi K, Nakagaki T, Koyama R, et al. Identification and characterization of the intercellular adhesion molecule-2 gene as a novel p53 target. Oncotarget. 2016;7:61426-61437 pubmed publisher
Qu Y, Zhou B, Yang W, Han B, Yu Rice Y, Gao B, et al. Transcriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs. Sci Rep. 2016;6:32007 pubmed publisher

product information

Catalog Number :

GTX102425

Product Name :

p63 antibody [N2C1], Internal

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary Antibody

list of Pubmed id :

23583370,24662128,27550649,27556181,28510629,28794159,28794006,29057977,29055049,29544077,29656943,29620279,29587142

Background :

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq]