POM121 antibody [N2N3] | GeneTex GTX102128 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

POM121 antibody [N2N3]

catalog :

GTX102128

quantity :

100.00μl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:500; loading ...; fig s1c	McCloskey A, Ibarra A, Hetzer M. Tpr regulates the total number of nuclear pore complexes per cell nucleus. Genes Dev. 2018;32:1321-1331 pubmed publisher
immunocytochemistry; human; 1:500; fig 2 western blot; human; 1:1000; fig 1 western blot; rat; 1:1000; fig 1	Franks T, Benner C, Narvaiza I, Marchetto M, Young J, Malik H, et al. Evolution of a transcriptional regulator from a transmembrane nucleoporin. Genes Dev. 2016;30:1155-71 pubmed publisher
western blot; human; fig 1b	Jiang P, Gan M, Yen S, Moussaud S, McLean P, Dickson D. Proaggregant nuclear factor(s) trigger rapid formation of ?-synuclein aggregates in apoptotic neurons. Acta Neuropathol. 2016;132:77-91 pubmed publisher

product information

Catalog No :

GTX102128

Product Name :

POM121 antibody [N2N3]

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μl

list of Pubmed id :

24196834,25602437

Product Description :

Rabbit Polyclonal antibody to POM121 (POM121 membrane glycoprotein (rat))

CrossReactivity :

Hu, Ms

Background :

The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is an integral membrane protein that localizes to the central spoke ring complex and participates in anchoring the nuclear pore complex to the nuclear envelope. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. [provided by RefSeq]

Immunogen :

Recombinant protein encompassing a sequence within the N-terminus region of human POM121. The exact sequence is proprietary.

Buffer :

1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Uses :

ICC/IF, IHC-P, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Image Legend_4 :

Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using POM121(GTX102128) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with GTX11305 (Red) at 1:500.

Image Legend_5 :

Immunohistochemical analysis of paraffin-embedded HBL435 xenograft, using POM121(GTX102128) antibody at 1:500 dilution.