alpha Cardiac Muscle Actin antibody | GeneTex GTX101876 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

alpha Cardiac Muscle Actin antibody

catalog :

GTX101876

quantity :

100.00μl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; rat; fig 2b	Unuma K, Aki T, Nagano S, Watanabe R, Uemura K. The down-regulation of cardiac contractile proteins underlies myocardial depression during sepsis and is mitigated by carbon monoxide. Biochem Biophys Res Commun. 2018;495:1668-1674 pubmed publisher

product information

Catalog No :

GTX101876

Product Name :

alpha Cardiac Muscle Actin antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μl

Product Description :

Rabbit Polyclonal antibody to alpha Cardiac Muscle Actin (actin, alpha, cardiac muscle 1)

CrossReactivity :

Hu, Ms, Rat

Background :

Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq]

Immunogen :

Recombinant protein encompassing a sequence within the center region of human alpha Cardiac Muscle Actin. The exact sequence is proprietary.

Buffer :

1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Uses :

ICC/IF, IHC-P, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Image Legend_4 :

alpha Actin (cardiac muscle) antibody detects alpha Actin (cardiac muscle) protein by western blot analysis. A. 30 μg PC-12 whole cell lysate/extract . B. 30 μg Rat2 whole cell lysate/extract. 10 % SDS-PAGE. alpha Actin (cardiac muscle) antibody (GTX101876) dilution: 1:10000

Image Legend_5 :

alpha Cardiac Muscle Actin antibody detects alpha Cardiac Muscle Actin protein by western blot analysis. Various whole cell extracts (30 μg) and Rat tissue extracts (50 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with alpha Cardiac Muscle Actin antibody (GTX101876) diluted at a dilution of 1:10000.