Calcium Sensing Receptor antibody | GeneTex GTX101348 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

Calcium Sensing Receptor antibody

catalog :

GTX101348

quantity :

100.00μl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

product information

Catalog No :

GTX101348

Product Name :

Calcium Sensing Receptor antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μl

list of Pubmed id :

25669848

Isotype :

IgG

Product Description :

Rabbit polyclonal antibody to Calcium Sensing Receptor (calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism))

CrossReactivity :

Background :

The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq]

Immunogen :

Recombinant protein encompassing a sequence within the center region of human Calcium Sensing Receptor. The exact sequence is proprietary.

Buffer :

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Uses :

ICC/IF, IHC-P, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.