Lamin A + C antibody | GeneTex GTX101127 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

Lamin A + C antibody

catalog :

GTX101127

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:1000; fig 5 western blot; human; 1:500; fig 5	Singh N, Johnstone D, Martin K, Tempera I, Kaplan M, Denny M. Alterations in nuclear structure promote lupus autoimmunity in a mouse model. Dis Model Mech. 2016;9:885-97 pubmed publisher
	Kuo C, Ling H, Chiang M, Chung C, Lee W, Chu C, et al. Metastatic Colorectal Cancer Rewrites Metabolic Program Through a Glut3-YAP-dependent Signaling Circuit. Theranostics. 2019;9:2526-2540 pubmed publisher
	Lee W, Chen P, Wu W, Wu H, Lan C, Huang Y, et al. Panobinostat sensitizes KRAS-mutant non-small-cell lung cancer to gefitinib by targeting TAZ. Int J Cancer. 2017;141:1921-1931 pubmed publisher
	Hung Y, Fang S, Wang S, Cheng W, Liu P, Su C, et al. Corylin protects LPS-induced sepsis and attenuates LPS-induced inflammatory response. Sci Rep. 2017;7:46299 pubmed publisher
	Ling H, Kuo C, Lin B, Huang Y, Lin C. Elevation of YAP promotes the epithelial-mesenchymal transition and tumor aggressiveness in colorectal cancer. Exp Cell Res. 2017;350:218-225 pubmed publisher
	Yang S, Lin S, Chen Y, Wu V, Yang W, Wu K. A low-salt diet increases the expression of renal sirtuin 1 through activation of the ghrelin receptor in rats. Sci Rep. 2016;6:32787 pubmed publisher
	Chen H, Lan Y, Li H, Cheng C, Lai P, Li W, et al. Urinary miR-16 transactivated by C/EBPÎ² reduces kidney function after ischemia/reperfusion-induced injury. Sci Rep. 2016;6:27945 pubmed publisher
	Kuo H, Liu P, Chong I, Liu Y, Chen Y, Ku P, et al. Pigment Epithelium-Derived Factor Mediates Autophagy and Apoptosis in Myocardial Hypoxia/Reoxygenation Injury. PLoS ONE. 2016;11:e0156059 pubmed publisher

product information

Catalog Number :

GTX101127

Product Name :

Lamin A + C antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary Antibody

list of Pubmed id :

24850735,24550138,24376600,28710768,24293369,22800509,23723143,24103751,24986919,25122478,26087007,27297958,27219009,27600292,27914787,25611434,28397806

Background :

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq]