This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
AKT1 antibody [N3C3]
catalog :
GTX101074
quantity :
100.00μl
price :
299 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
product information
Catalog No :
GTX101074
Product Name :
AKT1 antibody [N3C3]
Host Species :
Rabbit
Clonality :
Polyclonal
Product Type :
Primary antibody
Size :
100.00μl
List Price :
299 USD
Product Description :
Rabbit Polyclonal antibody to AKT1 (v-akt murine thymoma viral oncogene homolog 1)
CrossReactivity :
Hu
Background :
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
Immunogen :
Recombinant protein encompassing a sequence within the center region of human Akt1. The exact sequence is proprietary.
Buffer :
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Uses :
ICC/IF, IHC-P, WB
Concentration :
0.17mg/ml
General References :
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Image Legend_4 :
Sample (30 ug of whole cell lysate) A: A431 (GTX27909) 7.5% SDS PAGE GTX101074 diluted at 1:500
Image Legend_5 :
Akt1 antibody detects Akt1 protein at nucleus on human breast cacinoma by immunohistochemical analysis. Sample: Paraffin-embedded human breast cacinoma. Akt1 antibody (GTX101074) dilution: 1:500.
Image Legend_6 :
Akt1 antibody detects Akt1 protein at nucleus on human ovarian carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human ovarian carcinoma. Akt1 antibody (GTX101074) dilution: 1:500.
company information
GeneTex
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