SQSTM1 / P62 antibody [N3C1], Internal | GeneTex GTX100685 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

SQSTM1 / P62 antibody [N3C1], Internal

catalog :

GTX100685

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

citations: 16

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; loading ...; fig 2c western blot; human; loading ...; fig 1a	Lin T, Chan H, Chen S, Sarvagalla S, Chen P, Coumar M, et al. BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells. Autophagy. 2019;:1-18 pubmed publisher
	Jensen B, Schuldi M, McAvoy K, Russell K, Boehringer A, Curran B, et al. Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment. EMBO Mol Med. 2020;12:e10722 pubmed publisher
	Martello A, Lauriola A, Mellis D, Parish E, Dawson J, Imrie L, et al. Trichoplein binds PCM1 and controls endothelial cell function by regulating autophagy. EMBO Rep. 2020;21:e48192 pubmed publisher
	Chen J, Hsieh Y, Lo H, Li A, Chou C, Yang P. In Vitro and In Silico Mechanistic Insights into miR-21-5p-Mediated Topoisomerase Drug Resistance in Human Colorectal Cancer Cells. Biomolecules. 2019;9: pubmed publisher
	Yi H, Wang K, Du B, He L, Ho H, Qiu M, et al. Aleuritolic Acid Impaired Autophagic Flux and Induced Apoptosis in Hepatocellular Carcinoma HepG2 Cells. Molecules. 2018;23: pubmed publisher
	Liu G, Kung H, Chen C, Huang C, Wang Y, Yu C, et al. Improving nuclear envelope dynamics by EBV BFRF1 facilitates intranuclear component clearance through autophagy. FASEB J. 2018;32:3968-3983 pubmed publisher
	Chen C, Changou C, Hsieh T, Lee Y, Chu C, Hsu K, et al. Dual Inhibition of PIK3C3 and FGFR as a New Therapeutic Approach to Treat Bladder Cancer. Clin Cancer Res. 2018;24:1176-1189 pubmed publisher
	Lin S, Hsieh S, Fan Y, Wei W, Hsiao P, Tsai D, et al. Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance. Autophagy. 2018;14:778-795 pubmed publisher
	Hsin M, Hsieh Y, Wang P, Ko J, Hsin I, Yang S. Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells. Cell Death Dis. 2017;8:e3089 pubmed publisher
	Liu Y, Weng Y, Lin H, Tang S, Chen C, Liang C, et al. Aqueous extract of Polygonum bistorta modulates proteostasis by ROS-induced ER stress in human hepatoma cells. Sci Rep. 2017;7:41437 pubmed publisher
	Hai J, Zhu C, Wang T, Organ S, Shepherd F, Tsao M. TRIM14 is a Putative Tumor Suppressor and Regulator of Innate Immune Response in Non-Small Cell Lung Cancer. Sci Rep. 2017;7:39692 pubmed publisher
	Lappas M. The Adaptor Protein p62 Mediates Nuclear Factor ?B Activation in Response to Inflammation and Facilitates the Formation of Prolabor Mediators in Human Myometrium. Reprod Sci. 2017;24:762-772 pubmed publisher
	Tsai J, Hsu L, Huang H, Lin C, Pan M, Hong H, et al. 1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione Induces G1 Cell Cycle Arrest and Autophagy in HeLa Cervical Cancer Cells. Int J Mol Sci. 2016;17: pubmed publisher
	Tsai W, Lo Y, Wu M, Li C, Kuo Y, Lai Y, et al. Mycotoxin Patulin Suppresses Innate Immune Responses by Mitochondrial Dysfunction and p62/Sequestosome-1-dependent Mitophagy. J Biol Chem. 2016;291:19299-311 pubmed publisher
	Li H, Peng X, Wang Y, Cao S, Xiong L, Fan J, et al. Atg5-mediated autophagy deficiency in proximal tubules promotes cell cycle G2/M arrest and renal fibrosis. Autophagy. 2016;12:1472-86 pubmed publisher
	Hsu C, Qiu J, Chan Y. Cellular degradation activity is maintained during aging in long-living queen bees. Biogerontology. 2016;17:829-840 pubmed

product information

Catalog Number :

GTX100685

Product Name :

SQSTM1 / P62 antibody [N3C1], Internal

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary Antibody

list of Pubmed id :

23651616,23794287,24334178,25027955,25203626,25946033,23665396,27230748,27304991,27527160,27458013,27638291,28059079,28134285,24860144,28981104,29222162,29481305

Background :

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]