This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
PARP antibody
catalog :
GTX100573
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, chromatin immunoprecipitation
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1a
Chakraborty A, Tapryal N, Venkova T, Horikoshi N, Pandita R, Sarker A, et al. Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes. Nat Commun. 2016;7:13049 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 4c
Li G, Cunin P, Wu D, Diogo D, Yang Y, Okada Y, et al. The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1. PLoS Genet. 2016;12:e1006292 pubmed publisher
  • western blot; human; 1:1000; fig 5
Xu Y, Wu D, Zheng W, Yu F, Yang F, Yao Y, et al. Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. Oncotarget. 2016;7:6146-58 pubmed publisher
Bera R, Chiu M, Huang Y, Liang D, Lee Y, Shih L. Genetic and Epigenetic Perturbations by DNMT3A-R882 Mutants Impaired Apoptosis through Augmentation of PRDX2 in Myeloid Leukemia Cells. Neoplasia. 2018;20:1106-1120 pubmed publisher
Chen P, Tien H, Chen S, Horng C, Tang H, Jung H, et al. Response of Myeloid Leukemia Cells to Luteolin is Modulated by Differentially Expressed Pituitary Tumor-Transforming Gene 1 (PTTG1) Oncoprotein. Int J Mol Sci. 2018;19: pubmed publisher
Dominguez G, Maddelein M, Pucelle M, Nicaise Y, Maurage C, Duyckaerts C, et al. Neuronal sphingosine kinase 2 subcellular localization is altered in Alzheimer's disease brain. Acta Neuropathol Commun. 2018;6:25 pubmed publisher
Chang H, Lu C, Chiang J, Tsai F, Juan Y, Tsao J, et al. Pterostilbene modulates the suppression of multidrug resistance protein 1 and triggers autophagic and apoptotic mechanisms in cisplatin-resistant human oral cancer CAR cells via AKT signaling. Int J Oncol. 2018;: pubmed publisher
Lin S, Chu P, Liao W, Wu M, Tsui K, Lin L, et al. Glycyrrhizic acid induces human MDA-MB-231 breast cancer cell death and autophagy via the ROS-mitochondrial pathway. Oncol Rep. 2018;39:703-710 pubmed publisher
Li S, Chen C, Chen Y, Yen Y, Fang W, Tsai F, et al. Upregulation of CISD2 augments ROS homeostasis and contributes to tumorigenesis and poor prognosis of lung adenocarcinoma. Sci Rep. 2017;7:11893 pubmed publisher
Lee W, Chen P, Wu W, Wu H, Lan C, Huang Y, et al. Panobinostat sensitizes KRAS-mutant non-small-cell lung cancer to gefitinib by targeting TAZ. Int J Cancer. 2017;141:1921-1931 pubmed publisher
Tsui K, Wang P, Lin L, Li C. DHEA protects mitochondria against dual modes of apoptosis and necroptosis in human granulosa HO23 cells. Reproduction. 2017;154:101-110 pubmed publisher
Lee C, Chen P, Ho K, Shih C, Cheng C, Lin C, et al. The microRNA-302b-inhibited insulin-like growth factor-binding protein 2 signaling pathway induces glioma cell apoptosis by targeting nuclear factor IA. PLoS ONE. 2017;12:e0173890 pubmed publisher
Liang X, Shi H, Yang L, Qiu C, Lin S, Qi Y, et al. Inhibition of polypyrimidine tract-binding protein 3 induces apoptosis and cell cycle arrest, and enhances the cytotoxicity of 5- fluorouracil in gastric cancer cells. Br J Cancer. 2017;116:903-911 pubmed publisher
Chen P, Cheng C, Shih C, Ho K, Lin C, Lee C, et al. The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death. PLoS ONE. 2016;11:e0167096 pubmed publisher
Chen P, Chang C, Shih C, Cheng C, Lin C, Lee C, et al. The miR-204-3p-targeted IGFBP2 pathway is involved in xanthohumol-induced glioma cell apoptotic death. Neuropharmacology. 2016;110:362-375 pubmed publisher
Su T, Ku W, Chen H, Hsu Y, Hong Q, Chang G, et al. Oncogenic miR-137 contributes to cisplatin resistance via repressing CASP3 in lung adenocarcinoma. Am J Cancer Res. 2016;6:1317-30 pubmed
Shindo Y, Komatsu H, Hotta K, Ariga K, Oka K. An Artificial Reaction Promoter Modulates Mitochondrial Functions via Chemically Promoting Protein Acetylation. Sci Rep. 2016;6:29224 pubmed publisher
Zheng Y, Yin G, Le V, Zhang A, Chen S, Liang X, et al. Photodynamic-therapy Activates Immune Response by disrupting Immunity Homeostasis of Tumor Cells, which Generates Vaccine for Cancer Therapy. Int J Biol Sci. 2016;12:120-32 pubmed publisher
product information
Catalog Number :
GTX100573
Product Name :
PARP antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Product Type :
Primary Antibody
list of Pubmed id :
23091557,21907836,21708241,24812029,24641487,25027955,25040912,25596698,25914533,25909282,26363315,26238746,26160843,27374857,27487563,27429846,27626929,27703167,26431433,27893811,26722223,25949267,25436977,28323865,28624766,24569474,28928421,28710768,29207188,29512708,26716417,29649138,29615132
Background :
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq]
company information
GeneTex
2456 Alton Pkwy
Irvine, CA92606
info@genetex.com
http://www.genetex.com
1-877-436-3839
headquarters: USA