Rad51 antibody [N1C2] | GeneTex GTX100469 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

Rad51 antibody [N1C2]

catalog :

GTX100469

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, chromatin immunoprecipitation

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:500; loading ...; fig s7i	Kanakkanthara A, Jeganathan K, Limzerwala J, Baker D, Hamada M, Nam H, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016;353:1549-1552 pubmed
chromatin immunoprecipitation; human; loading ...; fig 4c western blot; human; loading ...; fig S7d	Chakraborty A, Tapryal N, Venkova T, Horikoshi N, Pandita R, Sarker A, et al. Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes. Nat Commun. 2016;7:13049 pubmed publisher
	Chen R, Lin C, Liang S, Villalobos O, Villaflores O, Lou B, et al. UVB Irradiation Induced Cell Damage and Early Onset of Junbb Expression in Zebrafish. Animals (Basel). 2020;10: pubmed publisher
	Peng Y, Liao Q, Tan W, Peng C, Hu Z, Chen Y, et al. The deubiquitylating enzyme USP15 regulates homologous recombination repair and cancer cell response to PARP inhibitors. Nat Commun. 2019;10:1224 pubmed publisher
	Li Y, Luo K, Yin Y, Wu C, Deng M, Li L, et al. USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response. Nat Commun. 2017;8:15752 pubmed publisher

product information

Catalog Number :

GTX100469

Product Name :

Rad51 antibody [N1C2]

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary Antibody

list of Pubmed id :

22778135,23724141,25035396,26683461,25733871,27703167,26396917,28569838,28569838

Background :

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. Transcript variants utilizing alternative polyA signals exist. [provided by RefSeq]