This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneCopoeia
product type :
protein
product name :
Human cysteine protease
catalog :
hRP-T3476-EF011
quantity :
25 ug
price :
145 USD
product information
Catalog :
hRP-T3476-EF011
volumne :
25 ug
symbol :
ATG4A
Name :
Human cysteine protease
description :
Cysteine protease ATG4A belongs to a member of the autophagin protein family. This protein is also designated as a member of the C-54 family of cysteine proteases. Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. Cysteine protease ATG4A cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP.
GenBank Accession :
NM_052936.1
Uniprot Accession :
Q8WYN0
application :
WB, ELISA, IP, antibody production, protein array
Fusion tag :
N-His
Peptide Length :
413aa(including fusion tag)
Molecular Weight :
47.3kDa(including fusion tag)
pI :
5.1
price :
145 USD
company information
GeneCopoeia
9620 Medical Center Drive
Rockville, MD 20850
inquiry@genecopoeia.com
www.genecopoeia.com
1-301-762-0888
headquarters: USA
GeneCopoeia offers the largest collection of expression-ready ORF cDNA, shRNA and miRNA clones. Available in a wide collection of lentiviral and non-viral expression vectors with a variety of fusion tags and reporters including fluorescent, solubility, purification and multi-functional tags. Explore the fully sequenced and expression-ready clone collections here.

Pre-validated gene-specific and miRNA qPCR primers are also available with reaction master mix reagents for quantitative analyses of gene or miRNA specific expression. SYBR Green® based qPCR mix kits together with pre-validated primers provide universal qPCR reaction conditions and robust qPCR data. Learn more about qPCR mix and primers.

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