This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneCopoeia
product type :
protein
product name :
Human mothers against decapentaplegic homolog 4
catalog :
hRP-B0219-EF011
quantity :
25 ug
price :
145 USD
product information
Catalog :
hRP-B0219-EF011
volumne :
25 ug
symbol :
SMAD4
Name :
Human mothers against decapentaplegic homolog 4
description :
This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bppalindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome.
GenBank Accession :
NM_005359.2
Uniprot Accession :
Q13485
application :
WB, ELISA, IP, antibody production, protein array
Fusion tag :
N-His
Peptide Length :
567aa(including fusion tag)
Molecular Weight :
62.3kDa(including fusion tag)
pI :
7.1
price :
145 USD
company information
GeneCopoeia
9620 Medical Center Drive
Rockville, MD 20850
inquiry@genecopoeia.com
www.genecopoeia.com
1-301-762-0888
headquarters: USA
GeneCopoeia offers the largest collection of expression-ready ORF cDNA, shRNA and miRNA clones. Available in a wide collection of lentiviral and non-viral expression vectors with a variety of fusion tags and reporters including fluorescent, solubility, purification and multi-functional tags. Explore the fully sequenced and expression-ready clone collections here.

Pre-validated gene-specific and miRNA qPCR primers are also available with reaction master mix reagents for quantitative analyses of gene or miRNA specific expression. SYBR Green® based qPCR mix kits together with pre-validated primers provide universal qPCR reaction conditions and robust qPCR data. Learn more about qPCR mix and primers.

Save time and publish faster on the GeneCopoeia Expressway to Discovery& number 8482;.