CKMT1A Polyclonal Antibody | Epigentek A70893-100 product information

product summary

company name :

Epigentek

product type :

antibody

product name :

CKMT1A Polyclonal Antibody

catalog :

A70893-100

quantity :

100 μl

price :

370.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Epigentek product webpage

product information

Catalog# :

A70893

Part # :

A70893-100

2022 Price (US) :

370.00 USD

Product Description (Product Name) :

CKMT1A Polyclonal Antibody

Size :

100 μl

Host :

Rabbit

Antigen (Uniprot Accession, Gene or prot ... :

CKMT1A

Conjugate :

Unconjugated

Clonality :

Polyclonal

Species/Reactivity :

Human, Mouse, Rat

Applications :

WB; Recommended dilution: WB 1:500 - 1:2000

Isotype :

IgG

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 258-417 of human CKMT1A (NP_001015001.1).

Shipping Temp :

Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles

Uniprot ID :

P12532

Gene :

CKMT1A

Storage Buffer :

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purity :

Affinity Purification

Alternative Names :

CKMT1A; CKMT1; U-MtCK; mia-CK; creatine kinase, mitochondrial 1A

Background :

Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.

more info or order :

Epigentek product webpage