NOX2-gp91phox Polyclonal Antibody | Epigentek A70477-100 product information

product summary

company name :

Epigentek

product type :

antibody

product name :

NOX2-gp91phox Polyclonal Antibody

catalog :

A70477-100

quantity :

100 μl

price :

370.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

Epigentek product webpage

product information

Catalog# :

A70477

Part # :

A70477-100

2022 Price (US) :

370.00 USD

Product Description (Product Name) :

NOX2-gp91phox Polyclonal Antibody

Size :

100 μl

Host :

Rabbit

Antigen (Uniprot Accession, Gene or prot ... :

NOX2 / gp91phox

Conjugate :

Unconjugated

Clonality :

Polyclonal

Species/Reactivity :

Human, Mouse, Rat

Applications :

WB, IHC, IF; Recommended dilution: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200

Isotype :

IgG

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 283-570 of human NOX2 / gp91phox (NP_000388.2).

Shipping Temp :

Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles

Uniprot ID :

P04839

Gene :

CYBB

Storage Buffer :

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purity :

Affinity Purification

Alternative Names :

CYBB; AMCBX2; CGD; GP91-1; GP91-PHOX; GP91PHOX; IMD34; NOX2; p91-PHOX; cytochrome b-245 beta chain

Background :

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

more info or order :

Epigentek product webpage