MRGPRX2 Polyclonal Antibody | Epigentek A66606-100 product information

product summary

company name :

Epigentek

product type :

antibody

product name :

MRGPRX2 Polyclonal Antibody

catalog :

A66606-100

quantity :

100 µl

price :

370.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry

more info or order :

Epigentek product webpage

product information

Catalog# :

A66606

Part # :

A66606-100

2022 Price (US) :

370.00 USD

Product Description (Product Name) :

MRGPRX2 Polyclonal Antibody

Size :

100 µl

Host :

Rabbit

Antigen (Uniprot Accession, Gene or prot ... :

MRGPRX2

Conjugate :

Unconjugated

Clonality :

Polyclonal

Species/Reactivity :

Human, Mouse

Applications :

ELISA, WB, IF; Recommended dilution:WB:1:1000-1:5000, IF:1:50-1:200

Isotype :

IgG

Immunogen :

Recombinant Human Mas-related G-protein coupled receptor member X2 protein (286-330AA)

Shipping Temp :

Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Uniprot ID :

Q96LB1

Gene :

MRGPRX2

Storage Buffer :

0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4

Purity :

Protein G purified

Alternative Names :

Mas-related G-protein coupled receptor member X2, MRGPRX2, MRGX2

Background :

Mast cell-specific receptor for basic secretagogues, i. e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction. Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.

more info or order :

Epigentek product webpage