SMG6 Polyclonal Antibody | Epigentek A65874-100 product information

product summary

company name :

Epigentek

product type :

antibody

product name :

SMG6 Polyclonal Antibody

catalog :

A65874-100

quantity :

100 µl

price :

370.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human

application :

ELISA, immunohistochemistry, immunocytochemistry

more info or order :

Epigentek product webpage

product information

Catalog# :

A65874

Part # :

A65874-100

2022 Price (US) :

370.00 USD

Product Description (Product Name) :

SMG6 Polyclonal Antibody

Size :

100 µl

Host :

Rabbit

Antigen (Uniprot Accession, Gene or prot ... :

SMG6

Conjugate :

Unconjugated

Clonality :

Polyclonal

Species/Reactivity :

Human

Applications :

ELISA, IHC, IF; Recommended dilution:IHC:1:20-1:200, IF:1:50-1:200

Isotype :

IgG

Immunogen :

Recombinant Human Telomerase-binding protein EST1A protein (251-511AA)

Shipping Temp :

Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Uniprot ID :

Q86US8

Gene :

SMG6

Storage Buffer :

0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4

Purity :

Protein G purified

Alternative Names :

Telomerase-binding protein EST1A, EST1-like protein A, Ever shorter telomeres 1A, Smg-6 homolog, Telomerase subunit EST1A, hSmg5/7a, SMG6, C17orf31, EST1A, KIAA0732

Background :

Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5'-(GTGTGG)(4)GTGT-3' telomeric DNA, but not to a telomerase RNA template component (TER).

more info or order :

Epigentek product webpage