ATG8 Polyclonal Antibody | Epigentek A65370-100 product information

product summary

company name :

Epigentek

product type :

antibody

product name :

ATG8 Polyclonal Antibody

catalog :

A65370-100

quantity :

100 µl

price :

370.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

application :

ELISA

more info or order :

Epigentek product webpage

product information

Catalog# :

A65370

Part # :

A65370-100

2022 Price (US) :

370.00 USD

Product Description (Product Name) :

ATG8 Polyclonal Antibody

Size :

100 µl

Host :

Rabbit

Antigen (Uniprot Accession, Gene or prot ... :

ATG8

Conjugate :

Unconjugated

Clonality :

Polyclonal

Species/Reactivity :

Candida glabrata

Applications :

ELISA

Isotype :

IgG

Immunogen :

Recombinant Candida glabrata Autophagy-related protein 8 protein (1-116AA)

Shipping Temp :

Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Uniprot ID :

Q6FXR8

Gene :

ATG8

Storage Buffer :

0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4

Purity :

Protein G purified

Alternative Names :

Autophagy-related protein 8, Autophagy-related ubiquitin-like modifier ATG8, ATG8, AUT7, CAGL0A04675g

Background :

Ubiquitin-like modifier involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation. With ATG4, mediates the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.

more info or order :

Epigentek product webpage