Histone H3K27ac (Acetyl H3K27) Polyclonal Antibody | Epigentek A-4708-100 product information

product summary

company name :

Epigentek

product type :

antibody

product name :

Histone H3K27ac (Acetyl H3K27) Polyclonal Antibody

catalog :

A-4708-100

quantity :

100 µl

price :

446.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation

more info or order :

Epigentek product webpage

citations: 1

Reference
Zhang W, Huang J, Cook D. Histone modification dynamics at H3K27 are associated with altered transcription of in planta induced genes in Magnaporthe oryzae. PLoS Genet. 2021;17:e1009376 pubmed publisher

product information

Catalog# :

A-4708

Part # :

A-4708-100

2022 Price (US) :

446.00 USD

Product Description (Product Name) :

Histone H3K27ac (Acetyl H3K27) Polyclonal Antibody

Size :

100 µl

Host :

Rabbit

Antigen (Uniprot Accession, Gene or prot ... :

Acetyl Histone H3K27

Conjugate :

Unconjugated

Clonality :

Polyclonal

Species/Reactivity :

Broad Range, Human, Mouse, Rat

Applications :

WB, IHC, IF, IP, ChIP, ChIPseq; Recommended dilution: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:200 ChIP 1:20 - 1:100 CHIPseq 1:20 - 1:100

Isotype :

IgG

Citations :

33534835

Immunogen :

Synthetic Peptide of Human Acetyl-Histone H3-K27

Shipping Temp :

Shipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.

Uniprot ID :

P68431

Gene :

H3K27ac

Storage Buffer :

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purity :

Affinity Purified

Alternative Names :

H3t, H3.4, H3/g, H3FT, H3K27ac

Background :

Histones are proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. Nucleosomes consist of about 146-147 bp of DNA wrapped around an octamer of histone proteins (histone 2A, histone 2B, histone 3, and histone 4). The N-terminal tails of histones protrude from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. The interaction of a linker histone, H1, with DNA between nucleosomes, facilitates the compaction of chromatin into higher-order structures. This gene is without introns and encodes a histone H3 family member. Transcripts from this gene are missing a polyA tail. As an alternative, they contain palindromic termination elements. This gene is located independently from the other H3 genes. Most H3 genes are found in the histone gene cluster on chromosome 6p22-p21. 3.

more info or order :

Epigentek product webpage