SIRT2 Polyclonal Antibody | Epigentek A-4702-100 product information

product summary

company name :

Epigentek

product type :

antibody

product name :

SIRT2 Polyclonal Antibody

catalog :

A-4702-100

quantity :

100 µl

price :

308.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

Epigentek product webpage

product information

Catalog# :

A-4702

Part # :

A-4702-100

2022 Price (US) :

308.00 USD

Product Description (Product Name) :

SIRT2 Polyclonal Antibody

Size :

100 µl

Host :

Rabbit

Antigen (Uniprot Accession, Gene or prot ... :

SIRT2

Conjugate :

Unconjugated

Clonality :

Polyclonal

Species/Reactivity :

Human, Mouse, Rat

Applications :

WB, IHC, IF; Recommended dilution: WB: 1:500-1:2000, IHC: 1:50-1:200, IF:1:10-1:100

Isotype :

IgG

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 288-389 of human SIRT2 (NP_036369.2).

Shipping Temp :

Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles

Uniprot ID :

Q8IXJ6

Gene :

SIRT2

Storage Buffer :

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purity :

Affinity Purification

Alternative Names :

SIR2, SIR2L, SIR2L2

Background :

SIRT2 (sirtuin homologue 2) is a member of the NAD-dependent histone deacetylase family of proteins (sirtuns) which are involved in a variety of cellular functions. These functions include gene silencing, histone deacetylation, chromosomal stability, and aging. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. SIRT2 is a human homolog of the yeast SIR2 and it acts as a transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clusters. This gene's expression rapidly increases during mitosis and is multiply phosphorylated at the G2/M transition of the cell cycle. SIRT2 is part of a phosphorylation cascade where it is phosphorylated late in G2, during M, and into the period of cytokinesis. SIRT2 appears to play an opposing role to SIRT1 in neurodegenerative diseases.

more info or order :

Epigentek product webpage