Histone H4K12ac (Acetyl H4K12) Polyclonal Antibody | Epigentek A-4029-100 product information

product summary

company name :

Epigentek

product type :

antibody

product name :

Histone H4K12ac (Acetyl H4K12) Polyclonal Antibody

catalog :

A-4029-100

quantity :

100 µl

price :

308.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

Epigentek product webpage

citations: 2

Reference
Lin J, Chen F, Sun M, Zhu J, Li Y, Pan L, et al. The relationship between apoptosis, chromatin configuration, histone modification and competence of oocytes: A study using the mouse ovary-holding stress model. Sci Rep. 2016;6:28347 pubmed publisher
Trapphoff T, Heiligentag M, Dankert D, Demond H, Deutsch D, FrÃ¶hlich T, et al. Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes. Hum Reprod. 2016;31:133-49 pubmed publisher

product information

Catalog# :

A-4029

Part # :

A-4029-100

2022 Price (US) :

308.00 USD

Product Description (Product Name) :

Histone H4K12ac (Acetyl H4K12) Polyclonal Antibody

Size :

100 µl

Host :

Rabbit

Antigen (Uniprot Accession, Gene or prot ... :

H4K12ac

Conjugate :

Unconjugated

Clonality :

Polyclonal

Species/Reactivity :

Human, Monkey, Mouse, Rat

Applications :

ELISA, IF, IHC, WB; Recommended dilution: WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000, ELISA:1:10000

Isotype :

IgG

Immunogen :

Synthesized peptide derived from Human Histone H4 around the acetylation site of K12

Shipping Temp :

Shipped at 4°C. Aliquot store at -20°C . Avoid repeated freeze / thaw cycles.

Uniprot ID :

P62805

Gene :

HIST1H4A

Storage Buffer :

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purity :

Affinity Purified

Alternative Names :

H4K12ac antibody, H4K12a antibody

Background :

Histone H4- along with H2A, H2B, and H3- is involved in the structure of chromatin in eukaryotic cells. Histone H4 can undergo several different types of epigenetic modifications that influence cellular processes. These modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation, occur on the N-terminal tail domains of histone H4, which results in remodeling of the nucleosome structure into an open conformation more accessible to transcription complexes. In most species, histone H4 is primarily acetylated at lysine 5, 8, 12, and 16.

more info or order :

Epigentek product webpage