Histone H3K56ac (Acetyl H3K56) Polyclonal Antibody | Epigentek A-4026-100 product information

product summary

company name :

Epigentek

product type :

antibody

product name :

Histone H3K56ac (Acetyl H3K56) Polyclonal Antibody

catalog :

A-4026-100

quantity :

100 µl

price :

411.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation

more info or order :

Epigentek product webpage

citations: 3

Reference
von Walden F, Liu C, Aurigemma N, Nader G. mTOR signaling regulates myotube hypertrophy by modulating protein synthesis, rDNA transcription, and chromatin remodeling. Am J Physiol Cell Physiol. 2016;311:C663-C672 pubmed publisher
Pal S, Graves H, Ohsawa R, Huang T, Wang P, Harmacek L, et al. The Commercial Antibodies Widely Used to Measure H3 K56 Acetylation Are Non-Specific in Human and Drosophila Cells. PLoS ONE. 2016;11:e0155409 pubmed publisher
Zhang Z, Ren S, Tan Y, Li Z, Tang X, Wang T, et al. Epigenetic regulation of NKG2D ligands is involved in exacerbated atherosclerosis development in Sirt6 heterozygous mice. Sci Rep. 2016;6:23912 pubmed publisher

product information

Catalog# :

A-4026

Part # :

A-4026-100

2022 Price (US) :

411.00 USD

Product Description (Product Name) :

Histone H3K56ac (Acetyl H3K56) Polyclonal Antibody

Size :

100 µl

Host :

Rabbit

Antigen (Uniprot Accession, Gene or prot ... :

H3K56ac

Conjugate :

Unconjugated

Clonality :

Polyclonal

Species/Reactivity :

Mouse, Rat, Human, Broad Range

Applications :

WB, IHC, IF, IP, ChIP, ChIPseq; Recommended dilution: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:200 ChIP 1:20 - 1:100 CHIPseq 1:20 - 1:100

Isotype :

IgG

Citations :

24012758, 27045575, 27187594, 27581648, 31110176, 33221996

Immunogen :

Synthetic Peptide of Human Acetyl-Histone H3-K56

Shipping Temp :

Shipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.

Uniprot ID :

Q16695

Gene :

HIST3H3

Storage Buffer :

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purity :

Affinity Purified

Alternative Names :

H3K56ac antibody, H3K56a antibody

Background :

Histone H3 along with H2A, H2B and H4 is involved in the structure of chromatin in eukaryotic cells. Histone H3 can undergo several different types of epigenetic modifications that influence cellular processes. These modifications, including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation, occur on the N-terminal tail domains of histone H3, which results in remodeling of the nucleosome structure into an open conformation more accessible to transcription complexes. In most species, histone H3 is primarily acetylated at lysine 9, 14, 18, 23, and can also be acetylated at lysine 56.

more info or order :

Epigentek product webpage