SMYD2 Polyclonal Antibody | Epigentek A-3730-100 product information

product summary

company name :

Epigentek

product type :

antibody

product name :

SMYD2 Polyclonal Antibody

catalog :

A-3730-100

quantity :

100 µl

price :

479.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human, mouse

application :

western blot

more info or order :

Epigentek product webpage

product information

Catalog# :

A-3730

Part # :

A-3730-100

2022 Price (US) :

479.00 USD

Product Description (Product Name) :

SMYD2 Polyclonal Antibody

Size :

100 µl

Host :

Rabbit

Antigen (Uniprot Accession, Gene or prot ... :

SMYD2

Conjugate :

Unconjugated

Clonality :

Polyclonal

Species/Reactivity :

Human, Mouse

Applications :

WB; Recommended dilution: WB 1:500 - 1:2000

Isotype :

IgG

Immunogen :

Synthetic Peptide of Human SMYD2

Shipping Temp :

Shipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.

Uniprot ID :

Q9NRG4

Gene :

SMYD2

Storage Buffer :

PBS with 0.02% sodium azide, pH7.3.

Purity :

Affinity Purified

Alternative Names :

KMT3C, HSKM-B, ZMYND14

Background :

SMYD2 (SET and MYND Domain Containing 2) is a member of the SMYD family of protein methyltransferases. All family members (SMYD1, SMYD2, SMYD3, SMYD4, and SMYD5) contain a conserved catalytic SET domain, first identified in Drosophila Su[var]3-9, Enhancer of zeste, and Trithorax proteins. Split by the MYN domain/zinc finger motif, this domain is believed to facilitate protein-protein interactions. SMYD2 localizes to cytoplasm and the nucleus and is also highly expressed in mouse heart, brain, liver, kidney, thymus, and ovary, as well as in the developing embryo of the mouse. SMYD2 is able to repress transcription by interacting with the Sin3A repressor complex and methylating lys36 of histone H3. SMYD2 also interacts with HSP90alpha and methylates lys4 of histone H3. Additionally, SMYD2 can methylate p53 at lys370 to repress p53-mediated transcriptional activation and apoptosis.

more info or order :

Epigentek product webpage