SETD2 Polyclonal Antibody | Epigentek A-3720-100 product information

product summary

company name :

Epigentek

product type :

antibody

product name :

SETD2 Polyclonal Antibody

catalog :

A-3720-100

quantity :

100 µl

price :

308.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

more info or order :

Epigentek product webpage

citations: 1

Reference
Zhou Y, Yan X, Feng X, Bu J, Dong Y, Lin P, et al. Setd2 regulates quiescence and differentiation of adult hematopoietic stem cells by restricting RNA polymerase II elongation. Haematologica. 2018;103:1110-1123 pubmed publisher

product information

Catalog# :

A-3720

Part # :

A-3720-100

2022 Price (US) :

308.00 USD

Product Description (Product Name) :

SETD2 Polyclonal Antibody

Size :

100 µl

Host :

Rabbit

Antigen (Uniprot Accession, Gene or prot ... :

SETD2

Conjugate :

Unconjugated

Clonality :

Polyclonal

Species/Reactivity :

Human, Mouse, Rat

Applications :

WB, IF; Recommended dilution: WB 1:500 - 1:2000; IF 1:50 - 1:200

Isotype :

IgG

Citations :

29650642

Immunogen :

Recombinant Protein of Human SETD2

Shipping Temp :

Shipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.

Uniprot ID :

Q9BYW2

Gene :

SETD2

Storage Buffer :

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purity :

Affinity Purified

Alternative Names :

HYPB, SET2, HIF-1, HIP-1, KMT3A, HBP231, HSPC069, p231HBP

Background :

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

more info or order :

Epigentek product webpage