Histone H3R8 Dimethyl Symmetric (H3R8me2s) Polyclonal Antibody | Epigentek A-3706-100 product information

product summary

company name :

Epigentek

product type :

antibody

product name :

Histone H3R8 Dimethyl Symmetric (H3R8me2s) Polyclonal Antibody

catalog :

A-3706-100

quantity :

100 µl

price :

419.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation

more info or order :

Epigentek product webpage

citations: 2

Reference
Kota S, Roening C, Patel N, Kota S, Baron R. PRMT5 inhibition promotes osteogenic differentiation of mesenchymal stromal cells and represses basal interferon stimulated gene expression. Bone. 2018;117:37-46 pubmed publisher
Xu J, Xu X, Wang B, Ma Y, Zhang L, Xu H, et al. Nuclear carbonic anhydrase 6B associates with PRMT5 to epigenetically promote IL-12 expression in innate response. Proc Natl Acad Sci U S A. 2017;114:8620-8625 pubmed publisher

product information

Catalog# :

A-3706

Part # :

A-3706-100

2022 Price (US) :

419.00 USD

Product Description (Product Name) :

Histone H3R8 Dimethyl Symmetric (H3R8me2s) Polyclonal Antibody

Size :

100 µl

Host :

Rabbit

Antigen (Uniprot Accession, Gene or prot ... :

Histone H3R8 Symmetric Dimethyl

Conjugate :

Unconjugated

Clonality :

Polyclonal

Species/Reactivity :

Human, Mouse, Rat, Broad Range

Applications :

WB, IHC, IF, IP, ChIP, ChIPseq; Recommended dilution: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200, IP 1:50 - 1:200, CHIP 1:20 - 1:50, CHIPseq 1:20 - 1:50

Isotype :

IgG

Immunogen :

Synthetic Peptide of Human Symmetric DiMethyl-Histone H3-R8

Shipping Temp :

Shipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.

Uniprot ID :

Q16695

Gene :

H3R8me2s

Storage Buffer :

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purity :

Affinity Purified

Alternative Names :

HIST3H3; H3.4; H3/g; H3FT; H3t; histone H3.1t

Background :

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3

more info or order :

Epigentek product webpage