EHMT2 Polyclonal Antibody | Epigentek A-3019-100 product information

product summary

company name :

Epigentek

product type :

antibody

product name :

EHMT2 Polyclonal Antibody

catalog :

A-3019-100

quantity :

100 µl

price :

403.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Epigentek product webpage

product information

Catalog# :

A-3019

Part # :

A-3019-100

2022 Price (US) :

403.00 USD

Product Description (Product Name) :

EHMT2 Polyclonal Antibody

Size :

100 µl

Host :

Rabbit

Antigen (Uniprot Accession, Gene or prot ... :

EHMT2

Conjugate :

Unconjugated

Clonality :

Polyclonal

Species/Reactivity :

Mouse, Rat, Human

Applications :

Isotype :

IgG

Immunogen :

Recombinant Protein of Human EHMT2

Shipping Temp :

Shipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.

Uniprot ID :

Q96KQ7

Gene :

EHMT2

Storage Buffer :

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purity :

Affinity Purified

Alternative Names :

EHMT2; BAT8; C6orf30; G9A; GAT8; KMT1C; NG36; histone-lysine N-methyltransferase EHMT2

Background :

EHMT2 (Euchromatic Histone Lysine Methyltransferase 2) is a histone methyltransferase that specifically mono- and dimethylates Lys-9 of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me is a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. This gene also mediates monomethylation of Lys-56 of histone H3 (H3K56me1) in G1 phase, promoting interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates Lys-27 of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Most likely targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. May also methylate histone H1. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of Lys-373 of p53/TP53. Also methylates CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6, KLF12 and itself.

more info or order :

Epigentek product webpage