MTA2 Polyclonal Antibody | Epigentek A-2742-100 product information

product summary

company name :

Epigentek

product type :

antibody

product name :

MTA2 Polyclonal Antibody

catalog :

A-2742-100

quantity :

100 µl

price :

479.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human, mouse, rat

application :

western blot, chromatin immunoprecipitation

more info or order :

Epigentek product webpage

product information

Catalog# :

A-2742

Part # :

A-2742-100

2022 Price (US) :

479.00 USD

Product Description (Product Name) :

MTA2 Polyclonal Antibody

Size :

100 µl

Host :

Rabbit

Antigen (Uniprot Accession, Gene or prot ... :

MTA2

Conjugate :

Unconjugated

Clonality :

Polyclonal

Species/Reactivity :

Human, Mouse, Rat

Applications :

WB, ChIP

Isotype :

IgG

Immunogen :

Recombinant Protein of Human MTA2

Shipping Temp :

Shipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.

Uniprot ID :

O94776

Gene :

MTA2

Storage Buffer :

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purity :

Affinity Purified

Alternative Names :

PID, MTA1L1

Background :

MTA2 (metastasis-associated protein) is a component of NuRD, a nucleosome remodeling deacetylase complex found in the nucleus of human cells. It demonstrates a very wide expression pattern and is highly expressed in various tissues. MTA2 represents only a single member of a small gene family that encode distinctive but related proteins involved in transcriptional regulation (either directly or indirectly). Chromatin remodeling may be an indirect effect of their transcriptional regulation. MTA2 is very similar to and shares domain types with another member of this family, a protein associated with metastatic carcinomas potential. The shared domains include two DNA binding domains, a dimerization domain, and a domain generally found in proteins that methylate DNA. A target protein for this gene is p53, and deacetylation of p53 is associated with reduced growth inhibition in transformed cells, thus indicating a role for these gene family members in metastasis.

more info or order :

Epigentek product webpage