| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:1000; fig s7d
| Hu D, Sun X, Magpusao A, Fedorov Y, Thompson M, Wang B, et al. Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease. Nat Commun. 2021;12:5305 pubmed publisher |
- immunocytochemistry; rat; loading ...; fig 1a
| Farías G, Fréal A, Tortosa E, Stucchi R, Pan X, Portegies S, et al. Feedback-Driven Mechanisms between Microtubules and the Endoplasmic Reticulum Instruct Neuronal Polarity. Neuron. 2019;102:184-201.e8 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5a
| Vodicka P, Chase K, Iuliano M, Tousley A, Valentine D, Sapp E, et al. Autophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice. J Huntingtons Dis. 2016;5:249-260 pubmed |
- immunohistochemistry - frozen section; mouse; 1:250; loading ...; fig 2c
| Oñate M, Catenaccio A, MartÃnez G, Armentano D, Parsons G, Kerr B, et al. Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury. Sci Rep. 2016;6:21709 pubmed publisher |
- immunohistochemistry - frozen section; mouse; fig 5
| Lian H, Litvinchuk A, Chiang A, Aithmitti N, Jankowsky J, Zheng H. Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease. J Neurosci. 2016;36:577-89 pubmed publisher |
- immunocytochemistry; human; fig 2
| Reisen F, Sauty De Chalon A, Pfeifer M, Zhang X, Gabriel D, Selzer P. Linking phenotypes and modes of action through high-content screen fingerprints. Assay Drug Dev Technol. 2015;13:415-27 pubmed publisher |
- immunohistochemistry; mouse; 1:200
| Jung H, Tatar A, Tu Y, Nobumori C, Yang S, Goulbourne C, et al. An absence of nuclear lamins in keratinocytes leads to ichthyosis, defective epidermal barrier function, and intrusion of nuclear membranes and endoplasmic reticulum into the nuclear chromatin. Mol Cell Biol. 2014;34:4534-44 pubmed publisher |
| McAlpine C, Beriault D, Behdinan T, Shi Y, Werstuck G. Oral glucosamine sulfate supplementation does not induce endoplasmic reticulum stress or activate the unfolded protein response in circulating leukocytes of human subjects. Can J Physiol Pharmacol. 2014;92:285-91 pubmed publisher |
| McAlpine C, Bowes A, Khan M, Shi Y, Werstuck G. Endoplasmic reticulum stress and glycogen synthase kinase-3? activation in apolipoprotein E-deficient mouse models of accelerated atherosclerosis. Arterioscler Thromb Vasc Biol. 2012;32:82-91 pubmed publisher |
| Golchoubian B, Brunner A, Bragulat Teixidor H, Neuner A, Akarlar B, Ozlu N, et al. Reticulon-like REEP4 at the inner nuclear membrane promotes nuclear pore complex formation. J Cell Biol. 2022;221: pubmed publisher |
| Bushell S, Pike A, Falzone M, Rorsman N, Ta C, Corey R, et al. The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K. Nat Commun. 2019;10:3956 pubmed publisher |
| Schiattarella G, Altamirano F, Tong D, French K, Villalobos E, Kim S, et al. Nitrosative stress drives heart failure with preserved ejection fraction. Nature. 2019;568:351-356 pubmed publisher |
| Walter F, O Brien A, Concannon C, Dussmann H, Prehn J. ER stress signaling has an activating transcription factor 6α (ATF6)-dependent "off-switch". J Biol Chem. 2018;293:18270-18284 pubmed publisher |
| Yamamoto Hino M, Katsumata E, Suzuki E, Maeda Y, Kinoshita T, Goto S. Nuclear envelope localization of PIG-B is essential for GPI-anchor synthesis in Drosophila. J Cell Sci. 2018;131: pubmed publisher |
| Richardson R, Ohlson M, Eitson J, Kumar A, McDougal M, Boys I, et al. A CRISPR screen identifies IFI6 as an ER-resident interferon effector that blocks flavivirus replication. Nat Microbiol. 2018;3:1214-1223 pubmed publisher |
| Lebeau P, Platko K, Al Hashimi A, Byun J, Lhotak S, Holzapfel N, et al. Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained. J Biol Chem. 2018;293:7329-7343 pubmed publisher |
| Tsuchiya Y, Saito M, Kadokura H, Miyazaki J, Tashiro F, Imagawa Y, et al. IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells. J Cell Biol. 2018;217:1287-1301 pubmed publisher |
| Bergmann T, Fregno I, Fumagalli F, Rinaldi A, Bertoni F, Boersema P, et al. Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides. J Biol Chem. 2018;293:5600-5612 pubmed publisher |
| Zhang J, Johnson J, He J, Napolitano G, Ramadass M, Rocca C, et al. Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A. J Biol Chem. 2017;292:10328-10346 pubmed publisher |
| Schaeffer C, Merella S, Pasqualetto E, Lazarevic D, Rampoldi L. Mutant uromodulin expression leads to altered homeostasis of the endoplasmic reticulum and activates the unfolded protein response. PLoS ONE. 2017;12:e0175970 pubmed publisher |
| Arno G, Agrawal S, Eblimit A, Bellingham J, Xu M, Wang F, et al. Mutations in REEP6 Cause Autosomal-Recessive Retinitis Pigmentosa. Am J Hum Genet. 2016;99:1305-1315 pubmed publisher |
| Taneike M, Nishida K, Omiya S, Zarrinpashneh E, Misaka T, Kitazume Taneike R, et al. mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy. PLoS ONE. 2016;11:e0152628 pubmed publisher |
| Niwa Y, Suzuki T, Dohmae N, Simizu S. Identification of DPY19L3 as the C-mannosyltransferase of R-spondin1 in human cells. Mol Biol Cell. 2016;27:744-56 pubmed publisher |
| Ulbrich L, Favaloro F, Trobiani L, Marchetti V, Patel V, Pascucci T, et al. Autism-associated R451C mutation in neuroligin3 leads to activation of the unfolded protein response in a PC12 Tet-On inducible system. Biochem J. 2016;473:423-34 pubmed publisher |
| Hotokezaka Y, Katayama I, van Leyen K, Nakamura T. GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses. Cell Death Dis. 2015;6:e1719 pubmed publisher |
| Ferron M, LaCombe J, Germain A, Oury F, Karsenty G. GGCX and VKORC1 inhibit osteocalcin endocrine functions. J Cell Biol. 2015;208:761-76 pubmed publisher |
| Jin H, Mimura N, Kashio M, Koseki H, Aoe T. Late-onset of spinal neurodegeneration in knock-in mice expressing a mutant BiP. PLoS ONE. 2014;9:e112837 pubmed publisher |
| Zhang L, Nosak C, Sollazzo P, Odisho T, Volchuk A. IRE1 inhibition perturbs the unfolded protein response in a pancreatic ?-cell line expressing mutant proinsulin, but does not sensitize the cells to apoptosis. BMC Cell Biol. 2014;15:29 pubmed publisher |
| Narise K, Okuda K, Enomoto Y, Hirayama T, Nagasawa H. Optimization of biguanide derivatives as selective antitumor agents blocking adaptive stress responses in the tumor microenvironment. Drug Des Devel Ther. 2014;8:701-17 pubmed publisher |
| Carlisle R, Brimble E, Werner K, Cruz G, Ask K, Ingram A, et al. 4-Phenylbutyrate inhibits tunicamycin-induced acute kidney injury via CHOP/GADD153 repression. PLoS ONE. 2014;9:e84663 pubmed publisher |
| Hossain G, Lynn E, Maclean K, Zhou J, Dickhout J, Lhotak S, et al. Deficiency of TDAG51 protects against atherosclerosis by modulating apoptosis, cholesterol efflux, and peroxiredoxin-1 expression. J Am Heart Assoc. 2013;2:e000134 pubmed publisher |
| Rosenberg Y, Sack M, Montefiori D, Forthal D, Mao L, Hernandez Abanto S, et al. Rapid high-level production of functional HIV broadly neutralizing monoclonal antibodies in transient plant expression systems. PLoS ONE. 2013;8:e58724 pubmed publisher |
| Tong X, Kita K, Chen S, Jiang X, Sugaya S, Jing W, et al. Involvement of heat shock protein 27 in the susceptibility of KT human breast cancer cells to UVC and interferon lethality. Exp Ther Med. 2012;4:913-917 pubmed |
| Patil H, Guruju M, Cho K, Yi H, Orry A, Kim H, et al. Structural and functional plasticity of subcellular tethering, targeting and processing of RPGRIP1 by RPGR isoforms. Biol Open. 2012;1:140-60 pubmed publisher |
| Schuiki I, Zhang L, Volchuk A. Endoplasmic reticulum redox state is not perturbed by pharmacological or pathological endoplasmic reticulum stress in live pancreatic ?-cells. PLoS ONE. 2012;7:e48626 pubmed publisher |
| Tyra H, Spitz D, Rutkowski D. Inhibition of fatty acid oxidation enhances oxidative protein folding and protects hepatocytes from endoplasmic reticulum stress. Mol Biol Cell. 2012;23:811-9 pubmed publisher |
| Apaja P, Xu H, Lukacs G. Quality control for unfolded proteins at the plasma membrane. J Cell Biol. 2010;191:553-70 pubmed publisher |
| Vitte J, Traver S, Maués De Paula A, Lesage S, Rovelli G, Corti O, et al. Leucine-rich repeat kinase 2 is associated with the endoplasmic reticulum in dopaminergic neurons and accumulates in the core of Lewy bodies in Parkinson disease. J Neuropathol Exp Neurol. 2010;69:959-72 pubmed publisher |
| Hartley T, Siva M, Lai E, Teodoro T, Zhang L, Volchuk A. Endoplasmic reticulum stress response in an INS-1 pancreatic beta-cell line with inducible expression of a folding-deficient proinsulin. BMC Cell Biol. 2010;11:59 pubmed publisher |
| Dobashi T, Tanabe S, Jin H, Mimura N, Yamamoto T, Nishino T, et al. BiP, an endoplasmic reticulum chaperone, modulates the development of morphine antinociceptive tolerance. J Cell Mol Med. 2010;14:2816-26 pubmed publisher |
| Clarke J, Emson P, Irvine R. Distribution and neuronal expression of phosphatidylinositol phosphate kinase IIgamma in the mouse brain. J Comp Neurol. 2009;517:296-312 pubmed publisher |
| Edwards T, Clowes V, Tsang H, Connell J, Sanderson C, Luzio J, et al. Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5. Biochem J. 2009;423:31-9 pubmed publisher |
| Sriburi R, Jackowski S, Mori K, Brewer J. XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. J Cell Biol. 2004;167:35-41 pubmed |
| Reimertz C, Kogel D, Rami A, Chittenden T, Prehn J. Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J Cell Biol. 2003;162:587-97 pubmed |
