This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
protein
product name :
AMH (human), (recombinant)
catalog :
ENZ-PRT195-0010
quantity :
10 µg
product information
Product ID :
ENZ-PRT195
Catalog Number :
ENZ-PRT195-0010
Product Name :
AMH (human), (recombinant)
Product Type :
Protein
Size :
10 µg
Image Legend 1 :
Coomassie stained SDS-PAGE. Lane 1: Molecular weight marker, Lane 2: 1.0 µg, Lane 3: 2.0 µg, Lane 4: 5.0 µg AMH (Prod. No. ENZ-PRT195).
Image Legend 2 :
Western blot analysis of AMH probed with mouse anti-HIS antibody. Lane 1: MWM, Lane 2: 100 ng AMH (Prod. No. ENZ-PRT195) probed HIS antibody.
Image Legend 3 :
Western blot analysis of AMH probed with rabbit anti-FLAG antibody. Lane 1: MWM, Lane 2: 100 ng AMH (Prod. No. ENZ-PRT195) probed FLAG antibody.
Image Legend 4 :
Caski cell growth inhibition assay after treatment with AMH (ENZ-PRT195): Caski cells were placed in stationary media at 5000 cells/well in 96 well plates. They were treated with a titered concentration of AMH diluted in cell culture media. The cells were grown at 37°C / 5% CO2 for 48 hours. Inhibition of growth was measured using a modified MTT cell viability assay. The ED50 range is between 0.05 - 1.0 μg/mL.
Background :
AMH (anti-Müllerian hormone) is a member of the TGF-β family of genes and has been shown to be present in both males and females. It is known to be expressed in Sertoli cells and is involved in male sexual differentiation. The hormone is present in the ovary of females and has been shown to be a marker of female fertility. AMH was found to inhibit primordial follicle assembly and decrease the initial primordial follicle pool size. Women with polycystic ovarian syndrome (PCOS) exhibit elevated levels of Anti-Müllerian hormone (AMH) which has been found to desensitize ovarian follicles. It has also been shown to inhibit growth of cervical cancer cells via the MIS type II receptor.
ALTnames :
anti-Müllerian hormone, Muellerian-inhibiting substance
Purity :
≥90% (SDS-PAGE)
Buffer :
Lyophilized in 1X PBS, pH 7.4.
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.